Intervertebral disc degeneration (IDD) and osteoarthritis (OA) affecting the facet joint of the
spine are biomechanically interdependent, typically occur in tandem, and have considerable …

Lumbar disc degeneration is one of the leading causes of chronic low back pain. The
degenerative cascade is often initiated by an imbalance between catabolic and anabolic …

Intervertebral disc degeneration (IVDD)‐induced lower back pain (LBP) is a common
problem worldwide. The underlying mechanism is partially accredited to ferroptosis, based …

Degeneration of the intervertebral disc (IVD) is a normal part of aging. Due to the spine's
declining function and the development of pain, it may affect one's physical health, mental …

Low back pain (LBP) is a major reason for disability, and symptomatic intervertebral disc
(IVD) degeneration (IDD) contributes to roughly 40% of all LBP cases. Current treatment …

Intervertebral disc degeneration (IDD) is the main contributor to low back pain, which is a
leading cause of disability worldwide. Although substantial progress has been made in …

Intervertebral disc (IVD) degeneration is a multifactorial pathological process associated
with low back pain, the leading cause of years lived in disability worldwide. Key …

A comprehensive understanding of the cellular heterogeneity and molecular mechanisms
underlying the development, homeostasis, and disease of human intervertebral disks (IVDs) …

This review article focuses on thermoresponsive hydrogels consisting of poloxamers which
are of high interest for biomedical application especially in drug delivery for ophthalmic …

Intervertebral disc (IVD) degeneration is frequently associated with low back and neck pain,
which accounts for disability worldwide. Despite the known outcomes of the IVD …