[HTML][HTML] Extracellular vesicles in nanomedicine and regenerative medicine: a review over the last decade

S Moghassemi, A Dadashzadeh, MJ Sousa, H Vlieghe… - Bioactive materials, 2024 - Elsevier
Small extracellular vesicles (sEVs) are known to be secreted by a vast majority of cells.
These sEVs, specifically exosomes, induce specific cell-to-cell interactions and can activate …

A Panorama of Extracellular Vesicle Applications: from biomarker detection to therapeutics

S Das, CJ Lyon, T Hu - ACS nano, 2024 - ACS Publications
Extracellular vesicles (EVs) secreted by all cell types are involved in the cell-to-cell transfer
of regulatory factors that influence cell and tissue phenotypes in normal and diseased …

Multiplexed analysis of EV reveals specific biomarker composition with diagnostic impact

JD Spitzberg, S Ferguson, KS Yang… - Nature …, 2023 - nature.com
Exosomes and extracellular vesicles (EV) are increasingly being explored as circulating
biomarkers, but their heterogenous composition will likely mandate the development of …

Single extracellular vesicle nanoscopy

A Saftics, S Abuelreich, E Romano… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) and their cargo constitute novel biomarkers. EV subpopulations
have been defined not only by abundant tetraspanins (eg, CD9, CD63 and CD81) but also …

Future of digital assays to resolve clinical heterogeneity of single extracellular vesicles

RTT Morales, J Ko - ACS nano, 2022 - ACS Publications
Extracellular vesicles (EVs) are complex lipid membrane vehicles with variable expressions
of molecular cargo, composed of diverse subpopulations that participate in the intercellular …

Thermophoretic glycan profiling of extracellular vesicles for triple-negative breast cancer management

Y Li, S Zhang, C Liu, J Deng, F Tian, Q Feng… - Nature …, 2024 - nature.com
Triple-negative breast cancer (TNBC) is a highly metastatic and heterogeneous type of
breast cancer with poor outcomes. Precise, non-invasive methods for diagnosis, monitoring …

ATP1A3 as a target for isolating neuron-specific extracellular vesicles from human brain and biofluids

Y You, Z Zhang, N Sultana, M Ericsson, YA Martens… - Science …, 2023 - science.org
Neuron-derived extracellular vesicles (NDEVs) are potential biomarkers of neurological
diseases although their reliable molecular target is not well established. Here, we …

MoS2-Plasmonic Nanocavities for Raman Spectra of Single Extracellular Vesicles Reveal Molecular Progression in Glioblastoma

M Jalali, C del Real Mata, L Montermini, O Jeanne… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are continually released from cancer cells into biofluids, carrying
actionable molecular fingerprints of the underlying disease with considerable diagnostic and …

CRISPR/Cas13a‐Based MicroRNA detection in tumor‐derived extracellular vesicles

JS Hong, T Son, CM Castro, H Im - Advanced Science, 2023 - Wiley Online Library
MicroRNAs (miRNAs) in extracellular vesicles (EVs) play essential roles in cancer initiation
and progression. Quantitative measurements of EV miRNAs are critical for cancer diagnosis …

Precise identification and profiling of surface proteins of ultra rare tumor specific extracellular vesicle with dynamic quantitative plasmonic imaging

C Zhai, J Long, J He, Y Zheng, B Wang, J Xu, Y Yang… - ACS …, 2023 - ACS Publications
Specific detection of tumor-derived EVs (tEVs) in plasma is complicated by nontumor EVs
and non-EV particles. To accurately identify tEVs and profile their surface protein expression …