In spite of great advances in cancer therapy, there is considerable current interest in
develo** anticancer agents with a new mode of action because of the development of …

Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …

Antibiotic resistance is increasing at a rate that far exceeds the pace of new development of
drugs. Antimicrobial peptides, both synthetic and from natural sources, have raised interest …

The growing problem of bacterial resistance to conventional antibiotic compounds and the
need for new antibiotics have stimulated interest in the development of antimicrobial …

A 21-residue peptide segment, LL7-27 (RKSKEKIGKEFKRIVQRIKDF), corresponding to
residues 7–27 of the only human cathelicidin antimicrobial peptide, LL37, is shown to exhibit …

Peptoids are an alternative approach to antimicrobial peptides that offer higher stability
towards enzymatic degradation. It is essential when develo** new types of peptoids, that …

Disruption of the cellular membrane by the amyloidogenic peptide IAPP (or amylin) has
been implicated in β-cell death during type 2 diabetes. While the structure of the mostly inert …

Synthetic peptides composed of multiples of the consensus heparin-binding Cardin and
Weintraub sequences AKKARA and ARKKAAKA are antimicrobial. Replacement of lysine …

Independently from the cell penetrating peptide uptake mechanism (endocytic or not), the
interaction of the peptide with the lipid bilayer remains a common issue that needs further …

The antibacterial effect of the endotoxin-binding Sushi peptides against Gram-negative
bacteria (GNB) is investigated in this study. Similar characteristics observed for Atomic force …