Nanoparticulation of prodrug into medicines for cancer therapy
Y Zhang, H Cui, R Zhang, H Zhang… - Advanced …, 2021 - Wiley Online Library
This article provides a broad spectrum about the nanoprodrug fabrication advances co‐
driven by prodrug and nanotechnology development to potentiate cancer treatment. The …
driven by prodrug and nanotechnology development to potentiate cancer treatment. The …
Merging data curation and machine learning to improve nanomedicines
Nanomedicine design is often a trial-and-error process, and the optimization of formulations
and in vivo properties requires tremendous benchwork. To expedite the nanomedicine …
and in vivo properties requires tremendous benchwork. To expedite the nanomedicine …
DrugMAP: molecular atlas and pharma-information of all drugs
The efficacy and safety of drugs are widely known to be determined by their interactions with
multiple molecules of pharmacological importance, and it is therefore essential to …
multiple molecules of pharmacological importance, and it is therefore essential to …
Amorphous solid dispersions (asds): The influence of material properties, manufacturing processes and analytical technologies in drug product development
R Iyer, V Petrovska Jovanovska, K Berginc, M Jaklič… - Pharmaceutics, 2021 - mdpi.com
Poorly water-soluble drugs pose a significant challenge to developability due to poor oral
absorption leading to poor bioavailability. Several approaches exist that improve the oral …
absorption leading to poor bioavailability. Several approaches exist that improve the oral …
Stimulus-responsive drug delivery nanoplatforms for inflammatory bowel disease therapy
J Long, X Liang, Z Ao, X Tang, C Li, K Yan, X Yu… - Acta Biomaterialia, 2024 - Elsevier
Inflammatory bowel disease (IBD) manifests as inflammation in the colon, rectum, and ileum,
presenting a global health concern with increasing prevalence. Therefore, effective anti …
presenting a global health concern with increasing prevalence. Therefore, effective anti …
Towards halal pharmaceutical: Exploring alternatives to animal-based ingredients
Halal is a crucial concept for Muslim consumers regarding consumed products, including
pharmaceutical ingredients, which are essential in modern medicine. To address the issue …
pharmaceutical ingredients, which are essential in modern medicine. To address the issue …
Pervasive transcriptome interactions of protein-targeted drugs
The off-target toxicity of drugs targeted to proteins imparts substantial health and economic
costs. Proteome interaction studies can reveal off-target effects with unintended proteins; …
costs. Proteome interaction studies can reveal off-target effects with unintended proteins; …
PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells
Immunolabeling and autoradiography have traditionally been applied as the methods-of-
choice to visualize and collect molecular information about physiological and pathological …
choice to visualize and collect molecular information about physiological and pathological …
Use of an antiviral mouthwash as a barrier measure in the SARS-CoV-2 transmission in adults with asymptomatic to mild COVID-19: a multicentre, randomized …
F Carrouel, M Valette, E Gadea, A Esparcieux… - Clinical Microbiology …, 2021 - Elsevier
Objectives To determine if commercially available mouthwash with β-cyclodextrin and citrox
(bioflavonoids)(CDCM) could decrease the severe acute respiratory syndrome coronavirus …
(bioflavonoids)(CDCM) could decrease the severe acute respiratory syndrome coronavirus …
Pharmaceutical agent cetylpyridinium chloride inhibits immune mast cell function by interfering with calcium mobilization
Cetylpyridinium chloride (CPC) is an antimicrobial used in numerous personal care and
janitorial products and food for human consumption at millimolar concentrations. Minimal …
janitorial products and food for human consumption at millimolar concentrations. Minimal …