Alpha-Glucosidase inhibitory peptides: Sources, preparations, identifications, and action mechanisms

H Lu, T **e, Q Wu, Z Hu, Y Luo, F Luo - Nutrients, 2023 - mdpi.com
With the change in people's lifestyle, diabetes has emerged as a chronic disease that poses
a serious threat to human health, alongside tumor, cardiovascular, and cerebrovascular …

Recent advances of α-glucosidase inhibitors: A comprehensive review

N Agrawal, M Sharma, S Singh… - Current topics in …, 2022 - ingentaconnect.com
Background: Diabetes mellitus (DM) is a critical health issue prevailing in nearly half a
billion people worldwide. It is one of the most threatening metabolic diseases. Type 2 DM is …

Synthesis, biological evaluation and molecular modelling of 3-Formyl-6-isopropylchromone derived thiosemicarbazones as α-glucosidase inhibitors

R Basri, S Ullah, A Khan, SN Mali, O Abchir, S Chtita… - Bioorganic …, 2023 - Elsevier
Abstract Type-2 Diabetes Mellitus (T2DM) is one of the most common metabolic disorders in
the world and over the past three decades its incidence has increased drastically. α …

[HTML][HTML] Phytochemical profile and antioxidant capacity, α-amylase and α-glucosidase inhibitory activities of Oxalis pes-caprae extracts in alloxan-induced diabetic …

I Kabach, N Bouchmaa, Z Zouaoui, A Ennoury… - Biomedicine & …, 2023 - Elsevier
Diabetes and its complications are closely correlated with chronic hyperglycemia, causing
severe oxidative stress and leading to glycation reaction with formation of advanced …

Phytochemical Analysis, α‐Glucosidase and Amylase Inhibitory, and Molecular Docking Studies on Persicaria hydropiper L. Leaves Essential Oils

MH Mahnashi, YS Alqahtani, BA Alyami… - Evidence‐Based …, 2022 - Wiley Online Library
Objective. Medicinal plants and essentials oils are well known for diverse biological
activities including antidiabetic potential. This study was designed to isolate essential oils …

Novel α-Glucosidase Inhibitory Peptides Identified In Silico from Dry-Cured Pork Loins with Probiotics through Peptidomic and Molecular Docking Analysis

P Kęska, J Stadnik, A Łupawka, A Michalska - Nutrients, 2023 - mdpi.com
Diabetes mellitus is a serious metabolic disorder characterized by abnormal blood glucose
levels in the body. The development of therapeutic strategies for restoring and maintaining …

Design, synthesis, spectroscopic characterization, single crystal X-ray analysis, in vitro α-amylase inhibition assay, DPPH free radical evaluation and computational …

M Devi, P Kumar, R Singh, J Sindhu… - European Journal of …, 2023 - Elsevier
In our quest to design and develop N/O-containing inhibitors of α-amylase, we have tried to
synergize the inhibitory action of 1, 4-naphthoquinone, imidazole and 1, 2, 3-triazole motifs …

In Vitro Evaluation of α-amylase and α-glucosidase Inhibition of 2,3-Epoxyprocyanidin C1 and Other Constituents from Pterocarpus erinaceus Poir

RT Feunaing, AN Tamfu, AJY Gbaweng… - Molecules, 2022 - mdpi.com
Diabetes mellitus is a metabolic disorder which is one of the leading causes of mortality and
morbidities in elderly humans. Chronic diabetes can lead to kidney failure, blindness, limb …

In vitro α-glucosidase inhibitory activity of Tamarix nilotica shoot extracts and fractions

M Daou, NA Elnaker, MA Ochsenkühn, SA Amin… - Plos one, 2022 - journals.plos.org
α-glucosidase inhibitors represent an important class of type 2 antidiabetic drugs and they
act by lowering postprandial hyperglycemia. Today, only three synthetic inhibitors exist on …

Bioactive Compounds from Kalanchoe Genus Potentially Useful for the Development of New Drugs

LBS Nascimento, LM Casanova, SS Costa - Life, 2023 - mdpi.com
The genus Kalanchoe Adans.(Crassulaceae) is native to Madagascar and comprises 145
species, being naturalized in the tropics and cultivated worldwide. In addition to having …