COVID-19 vaccine development: milestones, lessons and prospects
M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …
Recent developments in the immunopathology of COVID‐19
There has been an important change in the clinical characteristics and immune profile of
Coronavirus disease 2019 (COVID‐19) patients during the pandemic thanks to the …
Coronavirus disease 2019 (COVID‐19) patients during the pandemic thanks to the …
Engineering poly (ethylene glycol) nanoparticles for accelerated blood clearance inhibition and targeted drug delivery
Surface modification with poly (ethylene glycol)(PEGylation) is an effective strategy to
improve the colloidal stability of nanoparticles (NPs) and is often used to minimize cellular …
improve the colloidal stability of nanoparticles (NPs) and is often used to minimize cellular …
Allergies and COVID‐19 vaccines: an ENDA/EAACI position paper
Background Anaphylaxis, which is rare, has been reported after COVID‐19 vaccination, but
its management is not standardized. Method Members of the European Network for Drug …
its management is not standardized. Method Members of the European Network for Drug …
The interplay between PEGylated nanoparticles and blood immune system
C Guo, H Yuan, Y Wang, Y Feng, Y Zhang, T Yin… - Advanced Drug Delivery …, 2023 - Elsevier
During the last two decades, an increasing number of reports have pointed out that the
immunogenicity of polyethylene glycol (PEG) may trigger accelerated blood clearance …
immunogenicity of polyethylene glycol (PEG) may trigger accelerated blood clearance …
Antibodies against poly (ethylene glycol) activate innate immune cells and induce hypersensitivity reactions to PEGylated nanomedicines
Nanomedicines and macromolecular drugs can induce hypersensitivity reactions (HSRs)
with symptoms ranging from flushing and breathing difficulties to hypothermia, hypotension …
with symptoms ranging from flushing and breathing difficulties to hypothermia, hypotension …
Lipid nanoparticle technologies for nucleic acid delivery: A nanoarchitectonics perspective
Lipid‐based nanoparticles have emerged as a clinically viable platform technology to
deliver nucleic acids for a wide range of healthcare applications. Within this scope, one of …
deliver nucleic acids for a wide range of healthcare applications. Within this scope, one of …
Role of basophils in a broad spectrum of disorders
K Miyake, J Ito, H Karasuyama - Frontiers in immunology, 2022 - frontiersin.org
Basophils are the rarest granulocytes and have long been overlooked in immunological
research due to their rarity and similarities with tissue-resident mast cells. In the last two …
research due to their rarity and similarities with tissue-resident mast cells. In the last two …
Experience with polyethylene glycol allergy‐guided risk management for COVID‐19 vaccine anaphylaxis
K Brockow, S Mathes, J Fischer, S Volc, U Darsow… - Allergy, 2022 - Wiley Online Library
Background Polyethylene glycol (PEG) may elicit anaphylaxis to COVID‐19 mRNA
vaccines, and guidance for patients at risk is needed. Methods In retrospective patients with …
vaccines, and guidance for patients at risk is needed. Methods In retrospective patients with …
Nanoparticle surface engineering with heparosan polysaccharide reduces serum protein adsorption and enhances cellular uptake
Nanoparticle modification with poly (ethylene glycol)(PEG) is a widely used surface
engineering strategy in nanomedicine. However, since the artificial PEG polymer may …
engineering strategy in nanomedicine. However, since the artificial PEG polymer may …