Ceramides are sphingolipids containing a sphingosine or a related base, to which a fatty
acid is linked through an amide bond. When incorporated into a lipid bilayer, ceramides …

Cell membranes are very complex biological systems including a large variety of lipids and
proteins. Therefore, they are difficult to extract and directly investigate with biophysical …

Lysosomes have become an important target for anticancer therapeutics because lysosomal
cell death bypasses the classical caspase-dependent apoptosis pathway, enabling the …

Endogenous PIEZO1 channels of native endothelium lack the hallmark inactivation often
seen when these channels are overexpressed in cell lines. Because prior work showed that …

Ceramide is the simplest precursor of sphingolipids and is involved in a variety of biological
functions ranging from apoptosis to the immune responses. Although ceramide is a minor …

Lipid raft disruption is an early event during skeletal muscle unloading. Ceramide (Cer)
serves as a signaling lipid that can contribute to lipid raft disturbance and muscle atrophy …

The mitochondrion is an essential organelle enclosed by two membranes whose
functionalities depend on their very specific protein and lipid compositions. Proteins from the …

Sperm morphometry is a part of the semen analysis based on CASA technology and has
shown a big role in the prediction of male fertility. This analysis implies the use of stain …

Ceramides are the central molecules in sphingolipid metabolism. In addition, they are
recognized as important modulators of cell function, playing key roles in several cellular …

Ceramides, a group of biologically active sphingolipids, have been described as the new
cholesterol given strong evidence linking high plasma ceramide with endothelial damage …