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Fluctuating selection and the determinants of genetic variation
Recent studies of cosmopolitan Drosophila populations have found hundreds to thousands
of genetic loci with seasonally fluctuating allele frequencies, bringing temporally fluctuating …
of genetic loci with seasonally fluctuating allele frequencies, bringing temporally fluctuating …
The roles of sexual selection and sexual conflict in sha** patterns of genome and transcriptome variation
Sexual dimorphism is one of the most prevalent, and often the most extreme, examples of
phenotypic variation within species, and arises primarily from genomic variation that is …
phenotypic variation within species, and arises primarily from genomic variation that is …
Balancing selection via life-history trade-offs maintains an inversion polymorphism in a seaweed fly
How natural diversity is maintained is an evolutionary puzzle. Genetic variation can be
eroded by drift and directional selection but some polymorphisms persist for long time …
eroded by drift and directional selection but some polymorphisms persist for long time …
Antagonistic pleiotropy in human disease
Between the 1930s and 1950s, scientists developed key principles of population genetics to
try and explain the aging process. Almost a century later, these aging theories, including …
try and explain the aging process. Almost a century later, these aging theories, including …
Beyond large-effect loci: large-scale GWAS reveals a mixed large-effect and polygenic architecture for age at maturity of Atlantic salmon
M Sinclair-Waters, J Ødegård, SA Korsvoll… - Genetics Selection …, 2020 - Springer
Background Understanding genetic architecture is essential for determining how traits will
change in response to evolutionary processes such as selection, genetic drift and/or gene …
change in response to evolutionary processes such as selection, genetic drift and/or gene …
The search for sexually antagonistic genes: Practical insights from studies of local adaptation and statistical genomics
Sexually antagonistic (SA) genetic variation—in which alleles favored in one sex are
disfavored in the other—is predicted to be common and has been documented in several …
disfavored in the other—is predicted to be common and has been documented in several …
[PDF][PDF] Sex-specific dominance of gene expression in seed beetles
P Kaufmann, JL Rönn, E Immonen… - Molecular biology and …, 2024 - academic.oup.com
When different alleles are favored in different environments, dominance reversal where
alternate alleles are dominant in the environment in which they are favored can generate net …
alternate alleles are dominant in the environment in which they are favored can generate net …
Pleiotropic fitness effects across sexes and ages in the Drosophila genome and transcriptome
HWS Wong, L Holman - Evolution, 2023 - academic.oup.com
Selection varies between categories of individuals, with far-reaching ramifications: Sex-
specific selection can impede or accelerate adaptation, and differences in selection between …
specific selection can impede or accelerate adaptation, and differences in selection between …
Limits to genomic divergence under sexually antagonistic selection
Since the autosomal genome is shared between the sexes, sex-specific fitness optima
present an evolutionary challenge. While sexually antagonistic selection might favor …
present an evolutionary challenge. While sexually antagonistic selection might favor …
Sexually antagonistic selection maintains genetic variance when sexual dimorphism evolves
Genetic variance (VG) in fitness related traits is often unexpectedly high, evoking the
question how VG can be maintained in the face of selection. Sexually antagonistic (SA) …
question how VG can be maintained in the face of selection. Sexually antagonistic (SA) …