Anti‐vascular endothelial growth factor for diabetic macular oedema

G Virgili, M Parravano, F Menchini… - Cochrane Database of …, 2014 - cochranelibrary.com
Background Diabetic macular oedema (DMO) is a common complication of diabetic
retinopathy. Although grid or focal laser photocoagulation has been shown to reduce the risk …

Persistent diabetic macular edema: Definition, incidence, biomarkers, and treatment methods

OA Sorour, ES Levine, CR Baumal, AG Elnahry… - Survey of …, 2023 - Elsevier
Intravitreal antivascular endothelial growth factor (anti-VEGF) treatment has drastically
improved the visual and anatomical outcomes in patients with diabetic macular edema …

OCT biomarkers as functional outcome predictors in diabetic macular edema treated with dexamethasone implant

D Zur, M Iglicki, C Busch, A Invernizzi, M Mariussi… - Ophthalmology, 2018 - Elsevier
Purpose Identification and characterization of patients with diabetic macular edema (DME)
are important for individualizing treatment and optimizing outcome. We investigated OCT …

Effect of adding dexamethasone to continued ranibizumab treatment in patients with persistent diabetic macular edema: a DRCR network phase 2 randomized clinical …

RK Maturi, AR Glassman, D Liu, RW Beck… - JAMA …, 2018 - jamanetwork.com
Importance Some eyes have persistent diabetic macular edema (DME) following anti–
vascular endothelial growth factor (anti-VEGF) therapy for DME. Subsequently adding …

[HTML][HTML] Early and long-term responses to anti–vascular endothelial growth factor therapy in diabetic macular edema: analysis of protocol I data

VH Gonzalez, J Campbell, NM Holekamp, S Kiss… - American journal of …, 2016 - Elsevier
Purpose To determine whether early visual acuity response to ranibizumab in diabetic
macular edema is associated with long-term outcome. Design Post hoc analysis of …

[HTML][HTML] Predictors of functional and anatomic outcomes in patients with diabetic macular edema treated with ranibizumab

R Sophie, N Lu, PA Campochiaro - Ophthalmology, 2015 - Elsevier
Objective To investigate baseline predictors of month 24 best-corrected visual acuity (BCVA)
and central foveal thickness (CFT) in patients with diabetic macular edema (DME) treated …

[HTML][HTML] Endpoints for clinical trials in ophthalmology

L Schmetterer, H Scholl, G Garhöfer… - Progress in Retinal and …, 2023 - Elsevier
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Optical coherence tomography in the management of diabetic macular oedema

SKH Szeto, TYY Lai, S Vujosevic, JK Sun… - Progress in Retinal and …, 2024 - Elsevier
Diabetic macular oedema (DMO) is the major cause of visual impairment in people with
diabetes. Optical coherence tomography (OCT) is now the most widely used modality to …

Diabetic macular edema: current understanding, pharmacologic treatment options, and develo** therapies

K Miller, JA Fortun - The Asia-Pacific Journal of Ophthalmology, 2018 - journals.lww.com
Diabetic retinopathy and diabetic macular edema comprise a major source of visual
disability throughout the developed world. The etiology and pathogenesis of macular edema …

Early response to anti–vascular endothelial growth factor and two-year outcomes among eyes with diabetic macular edema in protocol T

NM Bressler, WT Beaulieu, MG Maguire… - American journal of …, 2018 - Elsevier
Purpose Assess associations of 2-year visual acuity (VA) outcomes with VA and optical
coherence tomography central subfield thickness (CST) after 12 weeks of anti–vascular …