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A review of the molecular mechanisms underlying the development and progression of cardiac remodeling
Pathological molecular mechanisms involved in myocardial remodeling contribute to alter
the existing structure of the heart, leading to cardiac dysfunction. Among the complex …
the existing structure of the heart, leading to cardiac dysfunction. Among the complex …
Stem cell injections in knee osteoarthritis: a systematic review of the literature
Objective Stem cell injection for knee osteoarthritis (KOA) is an emerging new therapy, and
we aimed to review its evidence of efficacy. Design Systematic review. Eligibility criteria …
we aimed to review its evidence of efficacy. Design Systematic review. Eligibility criteria …
Global position paper on cardiovascular regenerative medicine
Based on the increasingly understood regenerative capacity of the human heart and
vascular system, 1 cardiovascular regenerative medicine (CRM) encompasses all potential …
vascular system, 1 cardiovascular regenerative medicine (CRM) encompasses all potential …
Umbrella reviews
Like Ulysses in the Greek mythology, physicians and researchers are destined to endlessly
wonder in the search for the truth. Sir Karl Pooper (1902–1994) in his philosophical treaty on …
wonder in the search for the truth. Sir Karl Pooper (1902–1994) in his philosophical treaty on …
No evidence for the use of stem cell therapy for tendon disorders: a systematic review
Introduction Stem cells have emerged as a new treatment option for tendon disorders. We
systematically reviewed the current evidence for stem cell therapy in tendon disorders …
systematically reviewed the current evidence for stem cell therapy in tendon disorders …
MiRroring the multiple potentials of MicroRNAs in acute myocardial infarction
At present, cardiovascular diseases are depicted to be the leading cause of death worldwide
according to the World Health Organization. In the future, projections predict that ischemic …
according to the World Health Organization. In the future, projections predict that ischemic …
[HTML][HTML] The microenvironment of decellularized extracellular matrix from heart failure myocardium alters the balance between angiogenic and fibrotic signals from …
Cardiac adverse remodeling is characterized by biological changes that affect the
composition and architecture of the extracellular matrix (ECM). The consequently disrupted …
composition and architecture of the extracellular matrix (ECM). The consequently disrupted …
Β-blockers treatment of cardiac surgery patients enhances isolation and improves phenotype of cardiosphere-derived cells
Β-blockers (BB) are a primary treatment for chronic heart disease (CHD), resulting in
prognostic and symptomatic benefits. Cardiac cell therapy represents a promising …
prognostic and symptomatic benefits. Cardiac cell therapy represents a promising …
RegenHeart: a time-effective, low-concentration, detergent-based method aiming for conservative decellularization of the whole heart organ
E Dal Sasso, R Menabò, D Agrillo… - ACS Biomaterials …, 2020 - ACS Publications
Heart failure is the worst outcome of all cardiovascular diseases and still represents
nowadays the leading cause of mortality with no effective clinical treatments, apart from …
nowadays the leading cause of mortality with no effective clinical treatments, apart from …
Stem cell spheroids and ex vivo niche modeling: rationalization and scaling-up
Improved protocols/devices for in vitro culture of 3D cell spheroids may provide essential
cues for proper growth and differentiation of stem/progenitor cells (S/PCs) in their niche …
cues for proper growth and differentiation of stem/progenitor cells (S/PCs) in their niche …