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Advances in the treatment of mucoepidermoid carcinoma
S Sama, T Komiya, AK Guddati - World Journal of Oncology, 2021 - pmc.ncbi.nlm.nih.gov
Mucoepidermoid carcinoma (MEC) represents 10-15% of salivary neoplasms. Due to their
low incidence, it is challenging to conduct clinical trials and develop treatment guidelines …
low incidence, it is challenging to conduct clinical trials and develop treatment guidelines …
A molecular guide to systemic therapy in salivary gland carcinoma
AN Weaver, S Lakritz, D Mandair, MB Ulanja… - Head & …, 2023 - Wiley Online Library
Salivary gland carcinomas (SGC) are a rare and variable group of head and neck cancers
with historically poor response to cytotoxic chemotherapy and immunotherapy in the …
with historically poor response to cytotoxic chemotherapy and immunotherapy in the …
Aberrantly activated AREG–EGFR signaling is required for the growth and survival of CRTC1–MAML2 fusion-positive mucoepidermoid carcinoma cells
Salivary gland tumors (SGT) are a group of highly heterogeneous head and neck
malignancies with widely varied clinical outcomes and no standard effective treatments. The …
malignancies with widely varied clinical outcomes and no standard effective treatments. The …
Advances and challenges in precision medicine in salivary gland cancer
G Lassche, W van Boxtel, MJL Ligtenberg… - Cancer treatment …, 2019 - Elsevier
Salivary gland cancer (SGC) is a rare malignancy consisting of 22 subtypes with different
genetic, histological and clinical characteristics. This rarity and heterogeneity makes …
genetic, histological and clinical characteristics. This rarity and heterogeneity makes …
Mucoepidermoid carcinoma of the salivary gland: demographics and comparative analysis in US children and adults with future perspective of management
Simple Summary Salivary gland tumors are rare among both pediatric and adult
populations. Mucoepidermoid carcinoma (MEC) is a common type of malignant salivary …
populations. Mucoepidermoid carcinoma (MEC) is a common type of malignant salivary …
Molecular targets in salivary gland cancers: a comprehensive genomic analysis of 118 mucoepidermoid carcinoma tumors
Introduction: Salivary gland carcinomas (SGC) are histologically diverse cancers and next-
generation sequencing (NGS) to identify key molecular targets is an important aspect in the …
generation sequencing (NGS) to identify key molecular targets is an important aspect in the …
Sensitizing mucoepidermoid carcinomas to chemotherapy by targeted disruption of cancer stem cells
Mucoepidermoid carcinoma (MEC) is the most common malignancy of salivary glands. The
response of MEC to chemotherapy is unpredictable, and recent advances in cancer biology …
response of MEC to chemotherapy is unpredictable, and recent advances in cancer biology …
Activation of the EGFR/ERK pathway in high-grade mucoepidermoid carcinomas of the salivary glands
B Lujan, S Hakim, S Moyano, A Nadal… - British journal of …, 2010 - nature.com
Background: Mucoepidermoid carcinoma (MEC) shows differences in biological behaviour
depending mainly on its histological grade. High-grade tumours usually have an aggressive …
depending mainly on its histological grade. High-grade tumours usually have an aggressive …
Clinicopathological significance of EGFR pathway gene mutations and CRTC1/3–MAML2 fusions in salivary gland mucoepidermoid carcinoma
M Morita, T Murase, Y Okumura, K Ueda… - …, 2020 - Wiley Online Library
Aims Mucoepidermoid carcinoma (MEC) is one of the most common salivary gland
carcinomas. Epidermal growth factor receptor (EGFR) signalling pathway gene mutations …
carcinomas. Epidermal growth factor receptor (EGFR) signalling pathway gene mutations …
[HTML][HTML] Salivary Gland Cancers in the Era of Molecular Analysis: The Role of Tissue and Liquid Biomarkers
E Broseghini, F Carosi, M Berti, S Compagno… - Cancers, 2025 - mdpi.com
Abstract Background: Salivary gland cancers (SGCs) are a rare and heterogeneous group of
malignancies, accounting for approximately 5% of head and neck cancers. Despite their …
malignancies, accounting for approximately 5% of head and neck cancers. Despite their …