What we can learn from a genetic rodent model about autism
Autism spectrum disorders (ASD) are complex neurodevelopmental disorders that are
caused by genetic and/or environmental impacts, often probably by the interaction of both …
caused by genetic and/or environmental impacts, often probably by the interaction of both …
[HTML][HTML] Shank postsynaptic scaffolding proteins in autism spectrum disorder: Mouse models and their dysfunctions in behaviors, synapses, and molecules
S Jung, M Park - Pharmacological Research, 2022 - Elsevier
Postsynaptic scaffolding proteins, which are major components of the postsynaptic density
(PSD) at excitatory synapses, include Shank, PSD-95, A-kinase anchoring protein, Homer …
(PSD) at excitatory synapses, include Shank, PSD-95, A-kinase anchoring protein, Homer …
LMT USV toolbox, a novel methodological approach to place mouse ultrasonic vocalizations in their behavioral contexts—a study in female and male C57BL/6J mice …
F de Chaumont, N Lemière, S Coqueran… - Frontiers in behavioral …, 2021 - frontiersin.org
Ultrasonic vocalizations (USVs) are used as a phenotypic marker in mouse models of
neuropsychiatric disorders. Nevertheless, current methodologies still require time …
neuropsychiatric disorders. Nevertheless, current methodologies still require time …
Ultrasonic vocalizations in mice: relevance for ethologic and neurodevelopmental disorders studies
M Premoli, M Memo, SA Bonini - Neural Regeneration Research, 2021 - journals.lww.com
Mice use ultrasonic vocalizations (USVs) to communicate each other and to convey their
emotional state. USVs have been greatly characterized in specific life phases and contexts …
emotional state. USVs have been greatly characterized in specific life phases and contexts …
Effect of propionic acid on the morphology of the amygdala in adolescent male rats and their behavior
Autism spectrum disorder is a group of life-long developmental syndromes, characterized by
stereotypic behavior, restricted, communication deficits, cognitive and social impairments …
stereotypic behavior, restricted, communication deficits, cognitive and social impairments …
A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum
Background DLG2, also known as postsynaptic density protein-93 (PSD-93) or chapsyn-
110, is an excitatory postsynaptic scaffolding protein that interacts with synaptic surface …
110, is an excitatory postsynaptic scaffolding protein that interacts with synaptic surface …
Differences in the expression of restricted repetitive behaviors in female and male BTBR T+ tf/J mice
DA Amodeo, AE Pahua, M Zarate, JA Taylor… - Behavioural brain …, 2019 - Elsevier
Autism spectrum disorder (ASD) is characterized by the expression of restricted repetitive
behaviors (RRBs) and impairments in social recognition and communication …
behaviors (RRBs) and impairments in social recognition and communication …
Sex-dependent social and repetitive behavior and neurochemical profile in mouse model of autism spectrum disorder
H Ferreira, AC Sousa, J Sereno, J Martins… - Metabolites, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by deficits
in social interaction, impaired communication, and repetitive behaviors. ASD presents a 3: 1 …
in social interaction, impaired communication, and repetitive behaviors. ASD presents a 3: 1 …
Shank3 Mice Carrying the Human Q321R Mutation Display Enhanced Self-Grooming, Abnormal Electroencephalogram Patterns, and Suppressed Neuronal …
Shank3, a postsynaptic scaffolding protein involved in regulating excitatory synapse
assembly and function, has been implicated in several brain disorders, including autism …
assembly and function, has been implicated in several brain disorders, including autism …
Missense mutation in the activation segment of the kinase CK2 models Okur-Chung neurodevelopmental disorder and alters the hippocampal glutamatergic synapse
JM Cruz-Gamero, D Ballardin, B Lecis, CL Zhang… - Molecular …, 2024 - nature.com
Exome sequencing has enabled the identification of causative genes of monogenic forms of
autism, amongst them, in 2016, CSNK2A1, the gene encoding the catalytic subunit of the …
autism, amongst them, in 2016, CSNK2A1, the gene encoding the catalytic subunit of the …