COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment

A Parasher - Postgraduate medical journal, 2021 - academic.oup.com
Background The severe acute respiratory syndrome (SARS) coronavirus-2 is a novel
coronavirus belonging to the family Coronaviridae and is now known to be responsible for …

[HTML][HTML] Immunopathology of Hyperinflammation in COVID-19

JN Gustine, D Jones - The American journal of pathology, 2021 - Elsevier
The rapid spread of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome–coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented …

Surviving sepsis campaign guidelines on the management of adults with coronavirus disease 2019 (COVID-19) in the ICU: first update

W Alhazzani, L Evans, F Alshamsi, MH Møller… - Critical care …, 2021 - journals.lww.com
BACKGROUND: The coronavirus disease 2019 pandemic continues to affect millions
worldwide. Given the rapidly growing evidence base, we implemented a living guideline …

Infectious Diseases Society of America Guidelines on the treatment and management of patients with COVID-19 (April 2020)

A Bhimraj, RL Morgan, AH Shumaker… - Clinical infectious …, 2024 - academic.oup.com
Background There are many pharmacologic therapies that are being used or considered for
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …

The epidemiology, diagnosis and treatment of COVID-19

P Zhai, Y Ding, X Wu, J Long, Y Zhong, Y Li - International journal of …, 2020 - Elsevier
In December 2019, the outbreak of the novel coronavirus disease (COVID-19) in China
spread worldwide, becoming an emergency of major international concern. SARS-CoV-2 …

The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China

Y Yang, F Peng, R Wang, K Guan, T Jiang, G Xu… - Journal of …, 2020 - Elsevier
The 2019-nCoV is officially called SARS-CoV-2 and the disease is named COVID-19. This
viral epidemic in China has led to the deaths of over 1800 people, mostly elderly or those …

[HTML][HTML] Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury

CD Russell, JE Millar, JK Baillie - The lancet, 2020 - thelancet.com
The 2019 novel coronavirus (2019-nCoV) outbreak is a major challenge for clinicians. The
clinical course of patients remains to be fully characterised, little data are available that …

Effect of dexamethasone on days alive and ventilator-free in patients with moderate or severe acute respiratory distress syndrome and COVID-19: the CoDEX …

BM Tomazini, IS Maia, AB Cavalcanti, O Berwanger… - Jama, 2020 - jamanetwork.com
Importance Acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019
(COVID-19) is associated with substantial mortality and use of health care resources …

The COVID-19 pandemic: a comprehensive review of taxonomy, genetics, epidemiology, diagnosis, treatment, and control

YA Helmy, M Fawzy, A Elaswad, A Sobieh… - Journal of clinical …, 2020 - mdpi.com
A pneumonia outbreak with unknown etiology was reported in Wuhan, Hubei province,
China, in December 2019, associated with the Huanan Seafood Wholesale Market. The …

American College of Rheumatology clinical guidance for multisystem inflammatory syndrome in children associated With SARS–CoV‐2 and hyperinflammation in …

LA Henderson, SW Canna, KG Friedman… - Arthritis & …, 2020 - Wiley Online Library
Objective To provide guidance on the management of multisystem inflammatory syndrome
in children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …