Molecular mechanisms associated with neurodegeneration of neurotropic viral infection

P Wongchitrat, T Chanmee, P Govitrapong - Molecular Neurobiology, 2024 - Springer
Viral infections of the central nervous system (CNS) cause variable outcomes from acute to
severe neurological sequelae with increased morbidity and mortality. Viral neuroinvasion …

Endoplasmic reticulum & mitochondrial calcium homeostasis: The interplay with viruses

S Panda, S Behera, MF Alam, GH Syed - Mitochondrion, 2021 - Elsevier
Abstract Calcium ions (Ca 2+) act as secondary messengers in a plethora of cellular
processes and play crucial role in cellular organelle function and homeostasis. The average …

Antiviral potential of melissa officinalis L.: a literature review

A Behzadi, S Imani, N Deravi… - Nutrition and …, 2023 - journals.sagepub.com
The use of synthetic drugs has increased in recent years; however, herbal medicine is yet
more trusted among a huge population worldwide; This could be due to minimal side effects …

Evaluation of a novel severe combined immunodeficiency mouse model for antiviral drug evaluation against Chandipura virus infection

S Kitaura, M Tobiume, M Kawahara, M Satoh, H Kato… - Antiviral Research, 2023 - Elsevier
Chandipura virus (CHPV) is a negative-sense single-stranded RNA virus known to cause
fatal encephalitis outbreaks in the Indian subcontinent. The virus displays tropism towards …

Studies on the sequential pathology of Kyasanur Forest Disease (KFD) in Mouse brain: KFD virus induces apoptosis of neurons in cerebrum and hippocampus

UK Srikanth, CB Marinaik, S Rao, AR Gomes… - Plos one, 2024 - journals.plos.org
The sequential pathology of Kyasanur forest disease (KFD) in mouse brain was assessed in
this study. Kyasanur forest disease virus (KFDV) strain P9605 used in this study was …

Chandipura virus dysregulates the expression of hsa-miR-21-5p to activate NF-κB in human microglial cells

N Pandey, M Rastogi, SK Singh - Journal of Biomedical Science, 2021 - Springer
Background Chandipura virus (CHPV) is a negative single-stranded RNA virus of the
Rhabdoviridae family. CHPV infection has been reported in Central and Western India …

MicroRNAs participate in the regulation of apoptosis and oxidative stress-related gene expression in rabbits infected with Lagovirus europaeus GI.1 and GI.2 …

E Ostrycharz, A Fitzner, A Kęsy, A Siennicka… - Frontiers in …, 2024 - frontiersin.org
MicroRNAs (miRs) are a group of small, 17–25 nucleotide, non-coding RNA that regulate
gene expression at the post-transcriptional level. To date, little is known about the molecular …

Regulation of Bombyx mori ferritin heavy-chain homolog on ROS induces multiple effects on BmNPV replication

LB Zhu, ZH Huang, S Ayaz, ZX Guo, B Ling… - International Journal of …, 2023 - Elsevier
Ferritin is an iron-binding protein composed of light-chain and heavy-chain homologs with a
molecular weight of about 500 kDa. Free iron ions significantly affect reactive oxygen …

Involvement of RIG-I pathway in neurotropic virus-induced acute flaccid paralysis and subsequent spinal motor neuron death

M Bhaskar, S Mukherjee, A Basu - MBio, 2021 - journals.asm.org
Poliomyelitis-like illness is a common clinical manifestation of neurotropic viral infections.
Functional loss and death of motor neurons often lead to reduced muscle tone and …