Metal complexes derived from bidentate ligands: Synthesis, catalytic and biological applications
This review focusses on metal complexes containing bidentate ligands. The development in
the synthesis and some applications of these complexes, reported mainly in the last two …
the synthesis and some applications of these complexes, reported mainly in the last two …
Regioselective synthesis and computational calculation studies of some new pyrazolyl‐pyridine and bipyridine derivatives
Abstract Starting from 3‐oxo‐N‐(3‐pyridyl) butanamide, as key intermediate, the title
compounds were synthesized in good yields. Reaction of the pyridine‐carboxamide 1 with …
compounds were synthesized in good yields. Reaction of the pyridine‐carboxamide 1 with …
Synthesis and in-silico studies of some new thiazole carboxamide derivatives with theoretical investigation
N A. Kheder, H Ather, D R. Emam… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Based on the tremendous pharmacological activities of compounds containing thiazole and
carboxamide moieties, the current study aims to prepare new series of thiazole, pyrazole …
carboxamide moieties, the current study aims to prepare new series of thiazole, pyrazole …
Biological activity evaluation of some new benzenesulphonamide derivatives
Bacterial resistance to antibiotics has become one of the most challenging problems of
infectious disease treatment. Ten new derivatives of benzenesulphonamide bearing …
infectious disease treatment. Ten new derivatives of benzenesulphonamide bearing …
Synthesis and characterization of some new pyridine-carboxamide derivatives of potential biological activities
A facile synthetic routes to access some new heterocyclic systems containing potent
pharmacophoric groups such as pyrazole, pyrazolo [5, 1-c]-1, 2, 4-triazine, 1, 2, 4-triazino [4 …
pharmacophoric groups such as pyrazole, pyrazolo [5, 1-c]-1, 2, 4-triazine, 1, 2, 4-triazino [4 …
A new one-pot synthesis of pseudopeptide connected to sulfonamide via the tandem N-sulfonylation/Ugi reactions
In this study, an efficient one-pot reaction is reported for the synthesis of a new class of
pseudopeptide connected to sulfonamide via a tandem N-sulfonylation/Ugi four-component …
pseudopeptide connected to sulfonamide via a tandem N-sulfonylation/Ugi four-component …
In Silico Binding of 2-Aminocyclobutanones to SARS-CoV-2 Nsp13 Helicase and Demonstration of Antiviral Activity
The landscape of viral strains and lineages of SARS-CoV-2 keeps changing and is currently
dominated by Delta and Omicron variants. Members of the latest Omicron variants, including …
dominated by Delta and Omicron variants. Members of the latest Omicron variants, including …
The therapeutic potential of phytol towards Trypanosoma congolense infection and the inhibitory effects against trypanosomal sialidase
The search for novel therapeutic candidates against animal trypanosomiasis is an ongoing
scientific endevour because of the negative impacts of the disease to the African livestock …
scientific endevour because of the negative impacts of the disease to the African livestock …
Cyclobutanone Inhibitors of Diaminopimelate Desuccinylase (DapE) as Potential New Antibiotics
Based on our previous success in using cyclobutanone derivatives as enzyme inhibitors, we
have designed and prepared a 37-member library of α-aminocyclobutanone amides and …
have designed and prepared a 37-member library of α-aminocyclobutanone amides and …
[HTML][HTML] In vitro antiplasmodium and antitrypanosomal activities, β-haematin formation inhibition, molecular docking and DFT computational studies of quinoline-urea …
OE Oyeneyin, R Moodley, C Mashaba, LF Garnie… - Heliyon, 2024 - cell.com
Quinoline-urea-benzothiazole hybrids exhibited low to sub-micromolar in vitro activities
against the Plasmodium falciparum (P. falciparum) 3D7 chloroquine (CQ)-sensitive strain …
against the Plasmodium falciparum (P. falciparum) 3D7 chloroquine (CQ)-sensitive strain …