Peptide–nanoparticle conjugates (PNCs) have recently emerged as a versatile tool for
biomedical applications. Synergism between the two promising classes of materials allows …

Ischemic stroke leads to high disability and mortality. The limited delivery efficiency of most
therapeutic substances is a major challenge for effective treatment of ischemic stroke …

Ischemic stroke (IS) is one of the leading causes of death and disability resulting in
inevitable burden globally. Ischemic injury initiates cascade of pathological events …

Either hypoxia in an acute ischemic stroke before thrombolysis or the oxygen-boost after
thrombolysis cause a high level of free radicals, resulting in successive injuries to …

Reactive oxygen species (ROS) play important roles in cell signaling and tissue
homeostasis, in which the level of ROS is critical through the equilibrium between ROS …

Upregulation of programmed death ligand 1 (PD-L1) allows cancer cells to evade antitumor
immunity. Despite tremendous efforts in develo** PD-1/PD-L1 immune checkpoint …

Nanozymes are artificial enzymes with high catalytic activity, low cost, and good
biocompatibility, and have received ever-increasing attention in recent years. Various …

Stroke is one of the major causes of death and severe disability worldwide. At present,
intravenous thrombolysis to restore blood flow at the ischemic part of the brain is the main …

Recent developments in exploring the biological enzyme mimicking properties in
nanozymes have opened a separate avenue, which provides a suitable alternative to the …

Ischemic stroke represents one of the most prevalent pathologies in humans and is a
leading cause of death and disability. Anti-thrombolytic therapy with tissue plasminogen …