LncRNAs have attracted lots of attentions from researchers worldwide in recent decades.
With the rapid advances in both experimental technology and computational prediction …

A large portion of the eukaryotic genome is transcribed as noncoding RNAs (ncRNAs).
While once thought of primarily as “junk,” recent studies indicate that a large number of …

Antisense transcription (transcription from the opposite strand to a protein-coding or sense
strand) has been ascribed roles in gene regulation involving degradation of the …

Expression of Snail1 in epithelial cells triggers an epithelial–mesenchymal transition (EMT).
Here, we demonstrate that the synthesis of Zeb2, a transcriptional repressor of E-cadherin, is …

Using high-density oligonucleotide arrays representing essentially all nonrepetitive
sequences on human chromosomes 21 and 22, we map the binding sites in vivo for three …

Plants respond and adapt to drought, cold and high-salinity stresses in order to survive. In
this study, we applied Arabidopsis Affymetrix tiling arrays to study the whole genome …

Transcription in mammalian cells can be assessed at a genome-wide level, but it has been
difficult to reliably determine whether individual transcripts are derived from the plus or …

Antisense transcription is widespread in many genomes; however, how much is functional is
hotly debated. We are investigating functionality of a set of long noncoding antisense …

An increasing number of eukaryotic genes are being found to have naturally occurring
antisense transcripts. Here we study the extent of antisense transcription in the human …

Long non-coding RNAs (lncRNAs) are a heterogeneous class of RNAs that are generally
defined as non-protein-coding transcripts longer than 200 nucleotides. Recently, an …