Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …

N-Glycoproteomics, the system-wide study of glycans asparagine-linked to protein carriers,
holds a unique and still largely untapped potential to provide deep insights into the …

Clear cell renal cell carcinomas (ccRCCs) represent∼ 75% of RCC cases and account for
most RCC-associated deaths. Inter-and intratumoral heterogeneity (ITH) results in varying …

Protein glycosylation, a complex and heterogeneous post-translational modification that is
frequently dysregulated in disease, has been difficult to analyse at scale. Here we report a …

Clear cell renal cell carcinoma (ccRCC), a common form of RCC, is responsible for the high
mortality rate of kidney cancer. Dysregulations of glycoproteins have been shown to …

Glycosylation is one of the most common and important protein modifications, and it
regulates the properties and functions of a wide range of proteins. Aberrant glycosylation is …

Aberrant glycosylation has gained significant interest for biomarker discovery. However, low
detectability, complex glycan structures, and heterogeneity present challenges in …

Ovalbumin (OVA) was modified by fructose (Fru) and galactose (Gal) to study the structure,
IgG/IgE binding capacity and effects on human intestinal microbiota of the conjugated …

This trends article provides an overview of the state of the art in the analysis of intact
glycopeptides by proteomics technologies based on LC–MS analysis. A brief description of …

Glycoproteome analysis at a site-specific level and proteome scale stands out as a highly
promising approach for gaining insights into the intricate roles of glycans in biological …