Improving curcumin bioavailability: Current strategies and future perspectives
Curcumin possesses a plethora of interesting pharmacological effects. Unfortunately, it is
also characterized by problematic drug delivery and scarce bioavailability, representing the …
also characterized by problematic drug delivery and scarce bioavailability, representing the …
Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs)
This overview highlights the emergent area of mechanochemical reactions for making active
pharmaceutical ingredients (APIs), and covers the latest advances in the recently …
pharmaceutical ingredients (APIs), and covers the latest advances in the recently …
Complexation of polyoxometalates with cyclodextrins
Although complexation of hydrophilic guests inside the cavities of hydrophobic hosts is
considered to be unlikely, we demonstrate herein the complexation between γ-and β …
considered to be unlikely, we demonstrate herein the complexation between γ-and β …
Recent advances in the pharmaceutical and biomedical applications of cyclodextrin-capped gold nanoparticles
The real problem in pharmaceutical preparation is drugs' poor aqueous solubility, low
permeability through biological membranes, and short biological t1/2. Conventional drug …
permeability through biological membranes, and short biological t1/2. Conventional drug …
Cyclodextrin inclusion complexes with antibiotics and antibacterial agents as drug-delivery systems—A pharmaceutical perspective
Cyclodextrins (CDs) are a family of cyclic oligosaccharides, consisting of a macrocyclic ring
of glucose subunits linked by α-1, 4 glycosidic bonds. The shape of CD molecules is similar …
of glucose subunits linked by α-1, 4 glycosidic bonds. The shape of CD molecules is similar …
Grinding as solvent-free green chemistry approach for cyclodextrin inclusion complex preparation in the solid state
Among the different techniques proposed for preparing cyclodextrin inclusion complex in the
solid state, mechanochemical activation by grinding appears as a fast, highly efficient …
solid state, mechanochemical activation by grinding appears as a fast, highly efficient …
Bicalutamide anticancer activity enhancement by formulation of soluble inclusion complexes with cyclodextrins
Bicalutamide (BCL) is a nonsteroidal antiandrogen drug that represents an alternative to
castration in the treatment of prostate cancer, due to its relatively long half-life and tolerable …
castration in the treatment of prostate cancer, due to its relatively long half-life and tolerable …
Guest inclusion by native cyclodextrins in solid state and solutions: A review
In many industrial applications, preparation of cyclodextrin (CD) inclusion complexes with
drugs, food additives, dyes and components of essence oils is performed in solid mixtures …
drugs, food additives, dyes and components of essence oils is performed in solid mixtures …
On the interactions of melatonin/β-cyclodextrin inclusion complex: A novel approach combining efficient semiempirical extended tight-binding (xTB) results with ab …
Melatonin (MT) is a molecule of paramount importance in all living organisms, due to its
presence in many biological activities, such as circadian (sleep–wake cycle) and seasonal …
presence in many biological activities, such as circadian (sleep–wake cycle) and seasonal …
Cyclodextrins as effective additives in AuNP-catalyzed reduction of nitrobenzene derivatives in a ball-mill
S Menuel, B Léger, A Addad, E Monflier, F Hapiot - Green Chemistry, 2016 - pubs.rsc.org
At the boundary between mechanochemistry, supramolecular chemistry and catalysis, the
present study explores the role of cyclodextrins (CDs) and other saccharide additives in the …
present study explores the role of cyclodextrins (CDs) and other saccharide additives in the …