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Advanced techniques for detecting protein misfolding and aggregation in cellular environments
Protein misfolding and aggregation, a key contributor to the progression of numerous
neurodegenerative diseases, results in functional deficiencies and the creation of harmful …
neurodegenerative diseases, results in functional deficiencies and the creation of harmful …
Opportunities and Challenges in Applying Solid‐State NMR Spectroscopy in Organic Mechanochemistry
In recent years it is shown that mechanochemical strategies can be beneficial in directed
conversions of organic compounds. Finding new reactions proved difficult, and due to the …
conversions of organic compounds. Finding new reactions proved difficult, and due to the …
Dipolar Recoupling in Rotating Solids
Magic angle spinning (MAS) nuclear magnetic resonance (NMR) has evolved significantly
over the past three decades and established itself as a vital tool for the structural analysis of …
over the past three decades and established itself as a vital tool for the structural analysis of …
Sensitivity-enhanced multidimensional solid-state NMR spectroscopy by optimal-control-based transverse mixing sequences
Recently, proton-detected magic-angle spinning (MAS) solid-state nuclear magnetic
resonance (NMR) spectroscopy has become an attractive tool to study the structure and …
resonance (NMR) spectroscopy has become an attractive tool to study the structure and …
Molecular architecture of chitin and chitosan-dominated cell walls in zygomycetous fungal pathogens by solid-state NMR
Q Cheng, MC Dickwella Widanage, JR Yarava… - Nature …, 2024 - nature.com
Zygomycetous fungal infections pose an emerging medical threat among individuals with
compromised immunity and metabolic abnormalities. Our pathophysiological understanding …
compromised immunity and metabolic abnormalities. Our pathophysiological understanding …
High and fast: NMR protein–proton side-chain assignments at 160 kHz and 1.2 GHz
M Callon, D Luder, AA Malär, T Wiegand, V Římal… - Chemical …, 2023 - pubs.rsc.org
The NMR spectra of side-chain protons in proteins provide important information, not only
about their structure and dynamics, but also about the mechanisms that regulate interactions …
about their structure and dynamics, but also about the mechanisms that regulate interactions …
Selective detection of intermediate-amplitude motion by solid-state NMR
The coexistence of rigid and mobile molecules or molecular segments abounds in
biomolecular assemblies. Examples include the carbohydrate-rich cell walls of plants and …
biomolecular assemblies. Examples include the carbohydrate-rich cell walls of plants and …
Selective methods promote protein solid-state NMR
B Han, J Yang, Z Zhang - The Journal of Physical Chemistry …, 2024 - ACS Publications
Solid-state nuclear magnetic resonance (ssNMR) is indispensable for studying the
structures, dynamics, and interactions of insoluble proteins in native or native-like …
structures, dynamics, and interactions of insoluble proteins in native or native-like …
Cellular applications of DNP solid‐state NMR–state of the art and a look to the future
D Beriashvili, J Zhou, Y Liu, GE Folkers… - … –A European Journal, 2024 - Wiley Online Library
Sensitivity enhanced dynamic nuclear polarization solid‐state NMR is emerging as a
powerful technique for probing the structural properties of conformationally homogenous …
powerful technique for probing the structural properties of conformationally homogenous …
The evolution of paramagnetic NMR as a tool in structural biology
Paramagnetic NMR data contain extremely accurate long-range information on
metalloprotein structures and, when used in the frame of integrative structural biology …
metalloprotein structures and, when used in the frame of integrative structural biology …