Latest advances in cryogel technology for biomedical applications

A Memic, T Colombani, LJ Eggermont… - Advanced …, 2019 - Wiley Online Library
There exists a technological need for advanced materials with improved properties for
emerging biomedical applications. Recent developments in macroporous materials have …

Past, present, and future of affinity-based cell separation technologies

K Bacon, A Lavoie, BM Rao, M Daniele, S Menegatti - Acta biomaterialia, 2020 - Elsevier
Progress in cell purification technology is critical to increase the availability of viable cells for
therapeutic, diagnostic, and research applications. A variety of techniques are now available …

Affinity monolith chromatography: A review of general principles and recent developments

S Poddar, S Sharmeen, DS Hage - Electrophoresis, 2021 - Wiley Online Library
Affinity monolith chromatography (AMC) is a liquid chromatographic technique that utilizes a
monolithic support with a biological ligand or related binding agent to isolate, enrich, or …

Injectable cryogels in biomedicine

D Çimen, MA Özbek, N Bereli, B Mattiasson, A Denizli - Gels, 2021 - mdpi.com
Cryogels are interconnected macroporous materials that are synthesized from a monomer
solution at sub-zero temperatures. Cryogels, which are used in various applications in many …

Current trends in affinity-based monoliths in microextraction approaches: A review

M Vergara-Barberan, EJ Carrasco-Correa… - Analytica Chimica …, 2019 - Elsevier
This article reviews the research contributions along the past five years concerning to
monolithic materials for the development of affinity-based sorbents in the field of …

Biomolecule-conjugated macroporous hydrogels for biomedical applications

H Thakar, SM Sebastian, S Mandal… - ACS Biomaterials …, 2019 - ACS Publications
Biomolecule-conjugated macroporous hydrogels have been investigated in the fields of
bioseparation, biocatalysts, bioreactors, cell therapy, tissue regeneration, and environmental …

Efficient DNA separation and purification via VIPS-constructed membrane adsorbers

Q Zhao, X Liang, C He - Chemical Engineering Journal, 2024 - Elsevier
Solid phase extraction is an effective method for the separation and purification of nucleic
acid molecules, which still suffers from high loss and low efficiency. Herein, a polyether …

Dilemma on plasmid DNA purification: Binding capacity vs selectivity

JFA Valente, JA Queiroz, F Sousa - Journal of Chromatography A, 2021 - Elsevier
Plasmid DNA chromatography is a powerful field in constant development and evolution.
The use of this technique is considered mandatory in the production of an efficient and safe …

Cryogels and Monoliths: Promising Tools for Chromatographic Purification of Nucleic Acids

J Ribeiro, MÂ Luís, B Rodrigues, FM Santos… - Gels, 2024 - mdpi.com
The increasing demand for highly pure biopharmaceuticals has put significant pressure on
the biotechnological industry to innovate in production and purification processes. Nucleic …

DNA adsorption via Co (II) immobilized cryogels

K Erol - Journal of Macromolecular Science, Part A, 2016 - Taylor & Francis
The separation and purification of important biomolecule deoxyribonucleic acid (DNA)
molecules are extremely important. The adsorption technique among these methods is …