Antibiotic-resistant bacteria are recognized as one of the leading causes of death in the
world. We proposed and successfully tested peptides with a new mechanism of …

In recent years, due to the aging of the population and the development of diagnostic
medicine, the number of identified diseases associated with the accumulation of amyloid …

The aggregation of medin forming aortic medial amyloid is linked to arterial wall
degeneration and cerebrovascular dysfunction. Elevated levels of arteriolar medin are …

The behavior of amphiphilic molecules such as lipids, peptides and their mixtures at the
air/water interface allow us to evaluate and visualize the arrangement formed in a confined …

Abstract Proteorhodopsins (PRs), bacterial light-driven outward proton pumps comprise the
first discovered and largest family of rhodopsins, they play a significant role in life on the …

Membrane proteins (MPs) play vital roles in the function of cells and are also major drug
targets. Structural information on proteins is vital for understanding their mechanism of …

Two-component systems (TCS) are widespread signaling systems present in all domains of
life. TCS typically consist of a signal receptor/transducer and a response regulator. The …

The amyloid-beta peptide (Aβ) is considered a key factor in Alzheimer's disease (AD) ever
since the discovery of the disease. The understanding of its damaging influence has …

Amylin or human islet amyloid polypeptide (hIAPP) is a small peptide co-secreted with
insulin. Its peripheral aggregation on the lipid bilayer leads to fibril formation. The formation …

Abstract TDP-43 (transactive-response DNA binding protein) amazes structural biologist as
its aberrant ubiquitinated cytosolic inclusions is largely involved in neurodegenerative …