Abstract Langerhans Cell Histiocytosis (LCH) is an orphan disease of clonal dendritic cells
which may affect any organ of the body. Most of the knowledge about the diagnosis and …

The purpose of this review is to provide an updated overview of the pathogenesis and
treatment of Langerhans cell histiocytosis (LCH). The pathogenesis of LCH remains obscure …

Background There is little data on treatment of Langerhans cell histiocytosis (LCH) in adults.
Available data is on small numbers of patients with short follow-up times and no comparison …

Background Vinblastine is the standard treatment for children with Langerhans cell
histiocytosis (LCH). Whether this treatment could be extended to adults with LCH is …

Histiocytic disorders are an exceptionally rare group of diseases with diverse manifestations
and a paucity of approved treatments, thereby leading to various challenges in their …

Pulmonary Langerhans cell (LC) histiocytosis (PLCH) has unknown cause and is a rare
neoplastic disorder characterized by the infiltration of lungs and various organs by bone …

Langerhans cell histiocytosis (LCH) is a rare disease characterized by clonal expansion of
CD1a+ CD207+ myeloid dendritic cells. The features of LCH are mainly described in …

Pulmonary Langerhans' cell histiocytosis (PLCH) is a rare disorder of unknown cause
characterised by the infiltration of the lungs and other organs by the bone marrow derived …

Langerhans cell histiocytosis (LCH) is a clonally derived neoplasm with a highly variable
clinical course. Although LCH was once considered a disorder of immune regulation, the …

Langerhans cell histiocytosis (LCH) has been previously thought of as a rare illness, but is
now increasingly diagnosed as a result of the more intensive investigations of patients with …