The complicated connections and cross talk between the skeletal system and the immune
system are attracting more attention, which is develo** into the field of Osteoimmunology …

Osteoblasts, which are bone-forming cells, play pivotal roles in bone modeling and
remodeling. Osteoblast differentiation, also known as osteoblastogenesis, is orchestrated by …

To date, the delivery of signaling molecules for bone regeneration has focused primarily on
factors that directly affect the bone formation pathways (osteoinduction) or that serve to …

Bone regeneration following injury is initiated by inflammatory signals and occurs in
association with infiltration by sensory nerve fibers. Together, these events are believed to …

Osteoimmunology is an interdisciplinary research field which combines the existing fields of
osteology (bone biology) and immunology under one umbrella. The observation that …

Distraction osteogenesis (DO) successfully induces large-scale skeletal tissue regeneration,
but it involves an undesirably long treatment period. A high-speed DO mouse model (H-DO) …

Inspired by the physiological events of the “wound healing cascade”, the integration of
biomaterials and growth factors is generally accepted as an emerging and powerful strategy …

Interleukin (IL)-3 has long been known for its hematopoietic properties. However, recent
evidence has expanded our understanding of IL-3 function by identifying IL-3 as a critical …

Bone provides mechanical support, and flexibility to the body as a structural frame work
along with mineral storage, homeostasis, and blood pH regulation. The repair and/or …

Skeletal disorders represent a variety of degenerative diseases that affect bone and
cartilage homeostasis. The regenerative capacity of bone is affected in osteoporosis …