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Malaria: biology and disease
Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …
cause of death and disease across many tropical and subtropical countries. Over the last …
Cell division in apicomplexan parasites
Toxoplasma gondii and Plasmodium falciparum are important human pathogens. These
parasites and many of their apicomplexan relatives undergo a complex developmental …
parasites and many of their apicomplexan relatives undergo a complex developmental …
PlasmoDB: a functional genomic database for malaria parasites
C Aurrecoechea, J Brestelli, BP Brunk… - Nucleic acids …, 2009 - academic.oup.com
Abstract PlasmoDB (http://PlasmoDB. org) is a functional genomic database for Plasmodium
spp. that provides a resource for data analysis and visualization in a gene-by-gene or …
spp. that provides a resource for data analysis and visualization in a gene-by-gene or …
Heterochromatin protein 1 secures survival and transmission of malaria parasites
NMB Brancucci, NL Bertschi, L Zhu, I Niederwieser… - Cell host & …, 2014 - cell.com
Clonally variant expression of surface antigens allows the malaria parasite Plasmodium
falciparum to evade immune recognition during blood stage infection and secure malaria …
falciparum to evade immune recognition during blood stage infection and secure malaria …
Antigenic Variation in Plasmodium falciparum
The persistence of the human malaria parasite Plasmodium falciparum during blood stage
proliferation in its host depends on the successive expression of variant molecules at the …
proliferation in its host depends on the successive expression of variant molecules at the …
PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum
The variant antigen Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1),
which is expressed on the surface of P. falciparum-infected red blood cells, is a critical …
which is expressed on the surface of P. falciparum-infected red blood cells, is a critical …
A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion
The asexual forms of the malaria parasite Plasmodium falciparum are adapted for chronic
persistence in human red blood cells, continuously evading host immunity using …
persistence in human red blood cells, continuously evading host immunity using …
Reconstructing immune phylogeny: new perspectives
GW Litman, JP Cannon, LJ Dishaw - Nature Reviews Immunology, 2005 - nature.com
Numerous studies of the mammalian immune system have begun to uncover profound
interrelationships, as well as fundamental differences, between the adaptive and innate …
interrelationships, as well as fundamental differences, between the adaptive and innate …
Common strategies for antigenic variation by bacterial, fungal and protozoan pathogens
KW Deitsch, SA Lukehart, JR Stringer - Nature Reviews Microbiology, 2009 - nature.com
The complex relationships between infectious organisms and their hosts often reflect the
continuing struggle of the pathogen to proliferate and spread to new hosts, and the need of …
continuing struggle of the pathogen to proliferate and spread to new hosts, and the need of …
Genome-wide analysis of heterochromatin associates clonally variant gene regulation with perinuclear repressive centers in malaria parasites
Clonally variant gene families underlie phenotypic plasticity in Plasmodium falciparum, a
process indispensable for survival of the pathogen in its human host. Differential …
process indispensable for survival of the pathogen in its human host. Differential …