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Advances in light microscopy for neuroscience
Since the work of Golgi and Cajal, light microscopy has remained a key tool for
neuroscientists to observe cellular properties. Ongoing advances have enabled new …
neuroscientists to observe cellular properties. Ongoing advances have enabled new …
Latest developments in microfluidic cell biology and analysis systems
The multidisciplinary field of micro total analysis systems (μTAS) also called “lab-on-a-chip”
has enormously expanded in the last 2 years. By cross referencing online keyword searches …
has enormously expanded in the last 2 years. By cross referencing online keyword searches …
High-throughput in vivo vertebrate screening
We demonstrate a high-throughput platform for cellular-resolution in vivo chemical and
genetic screens on zebrafish larvae. The system automatically loads zebrafish from …
genetic screens on zebrafish larvae. The system automatically loads zebrafish from …
Lens-free optical tomographic microscope with a large imaging volume on a chip
We present a lens-free optical tomographic microscope, which enables imaging a large
volume of approximately 15 mm3 on a chip, with a spatial resolution of< 1 μm×< 1 μm×< 3 …
volume of approximately 15 mm3 on a chip, with a spatial resolution of< 1 μm×< 1 μm×< 3 …
Lifespan-on-a-chip: microfluidic chambers for performing lifelong observation of C. elegans
This article describes the fabrication of a microfluidic device for the liquid culture of many
individual nematode worms (Caenorhabditis elegans) in separate chambers. Each chamber …
individual nematode worms (Caenorhabditis elegans) in separate chambers. Each chamber …
Large-scale microfluidics providing high-resolution and high-throughput screening of Caenorhabditis elegans poly-glutamine aggregation model
Next generation drug screening could benefit greatly from in vivo studies, using small animal
models such as Caenorhabditis elegans for hit identification and lead optimization. Current …
models such as Caenorhabditis elegans for hit identification and lead optimization. Current …
Chemistry and the Worm: Caenorhabditis elegans as a Platform for Integrating Chemical and Biological Research
This Review discusses the potential usefulness of the worm Caenorhabditis elegans as a
model organism for chemists interested in studying living systems. C. elegans, a 1 mm long …
model organism for chemists interested in studying living systems. C. elegans, a 1 mm long …
Long-term high-resolution imaging and culture of C. elegans in chip-gel hybrid microfluidic device for developmental studies
Developmental studies in multicellular model organisms such as Caernohabditis elegans
rely extensively on the ability to cultivate and image animals repeatedly at the cell or …
rely extensively on the ability to cultivate and image animals repeatedly at the cell or …
[HTML][HTML] Microfluidics as a tool for C. elegans research
Microfluidics has emerged as a set of powerful tools that have greatly advanced some areas
of biological research, including research using C. elegans. The use of microfluidics has …
of biological research, including research using C. elegans. The use of microfluidics has …
Laser microsurgery in Caenorhabditis elegans
Laser killing of cell nuclei has long been a powerful means of examining the roles of
individual cells in C. elegans. Advances in genetics, laser technology, and imaging have …
individual cells in C. elegans. Advances in genetics, laser technology, and imaging have …