UEG position paper on pancreatic cancer. Bringing pancreatic cancer to the 21st century: Prevent, detect, and treat the disease earlier and better
Background Pancreatic ductal adenocarcinoma is the deadliest cancer worldwide with a
98% loss‐of‐life expectancy and a 30% increase in the disability‐adjusted life years during …
98% loss‐of‐life expectancy and a 30% increase in the disability‐adjusted life years during …
Germline genetic variability in pancreatic cancer risk and prognosis
Pancreatic cancer (PC), particularly its most common form, pancreatic ductal
adenocarcinoma (PDAC), is relatively rare but highly lethal. Knowledge about PC risk …
adenocarcinoma (PDAC), is relatively rare but highly lethal. Knowledge about PC risk …
[HTML][HTML] Genetic and non-genetic risk factors for early-onset pancreatic cancer
Y Nodari, M Gentiluomo… - Digestive and Liver …, 2023 - Elsevier
Background Early-onset pancreatic cancer (EOPC) represents 5–10% of all pancreatic
ductal adenocarcinoma (PDAC) cases, and the etiology of this form is poorly understood. It …
ductal adenocarcinoma (PDAC) cases, and the etiology of this form is poorly understood. It …
Association between a polymorphic variant in the CDKN2B‐AS1/ANRIL gene and pancreatic cancer risk
M Giaccherini, R Farinella… - … Journal of Cancer, 2023 - Wiley Online Library
Genes carrying high‐penetrance germline mutations may also be associated with cancer
susceptibility through common low‐penetrance genetic variants. To increase the knowledge …
susceptibility through common low‐penetrance genetic variants. To increase the knowledge …
[HTML][HTML] The local environment and germline genetic variation predict cancer risk in the UK Biobank prospective cohort
Background There is a growing body of evidence on the effect of the local environment
exposure on cancer susceptibility. Nonetheless, several of the associations remain …
exposure on cancer susceptibility. Nonetheless, several of the associations remain …
Polymorphic variants involved in methylation regulation: a strategy to discover risk loci for pancreatic ductal adenocarcinoma
Introduction Only a small number of risk factors for pancreatic ductal adenocarcinoma
(PDAC) has been established. Several studies identified a role of epigenetics and of …
(PDAC) has been established. Several studies identified a role of epigenetics and of …
Clinical prediction models for pancreatic cancer in general and at-risk populations: a systematic review
R Santos, HG Coleman, V Cairnduff… - Official journal of the …, 2023 - journals.lww.com
METHODS: MEDLINE, Embase, and Web of Science were searched for relevant articles
from the inception of each database up to November 2021. Study selection and data …
from the inception of each database up to November 2021. Study selection and data …
Germline aberrations in pancreatic cancer: implications for clinical care
Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor prognosis and represents
a major public health issue, as both its incidence and mortality are expecting to increase …
a major public health issue, as both its incidence and mortality are expecting to increase …
Diabetes Mellitus in Pancreatic Cancer: A Distinct Approach to Older Subjects with New-Onset Diabetes Mellitus
J Bures, D Kohoutova, J Skrha, B Bunganic, O Ngo… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma remains one of the most serious
malignancies and a leading cause of cancer-related deaths worldwide. There are no …
malignancies and a leading cause of cancer-related deaths worldwide. There are no …
Role of pancreatic ductal adenocarcinoma risk factors in intraductal papillary mucinous neoplasm progression
Introduction Pancreatic ductal adenocarcinoma (PDAC) is lethal due to its late diagnosis
and lack of successful treatments. A possible strategy to reduce its death burden is …
and lack of successful treatments. A possible strategy to reduce its death burden is …