Background Pancreatic ductal adenocarcinoma is the deadliest cancer worldwide with a
98% loss‐of‐life expectancy and a 30% increase in the disability‐adjusted life years during …

Pancreatic cancer (PC), particularly its most common form, pancreatic ductal
adenocarcinoma (PDAC), is relatively rare but highly lethal. Knowledge about PC risk …

Background Pancreatic cancer (PC) is influenced by both genetic and lifestyle factors.
However, further research is still needed to comprehensively clarify the relationships among …

Background Early-onset pancreatic cancer (EOPC) represents 5–10% of all pancreatic
ductal adenocarcinoma (PDAC) cases, and the etiology of this form is poorly understood. It …

Genes carrying high‐penetrance germline mutations may also be associated with cancer
susceptibility through common low‐penetrance genetic variants. To increase the knowledge …

Introduction Only a small number of risk factors for pancreatic ductal adenocarcinoma
(PDAC) has been established. Several studies identified a role of epigenetics and of …

Introduction Pancreatic ductal adenocarcinoma (PDAC) is lethal due to its late diagnosis
and lack of successful treatments. A possible strategy to reduce its death burden is …

Background There is a growing body of evidence on the effect of the local environment
exposure on cancer susceptibility. Nonetheless, several of the associations remain …

Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor prognosis and represents
a major public health issue, as both its incidence and mortality are expecting to increase …

Simple Summary Pancreatic ductal adenocarcinoma remains one of the most serious
malignancies and a leading cause of cancer-related deaths worldwide. There are no …