In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

Stem cells can be defined as units of biological organization that are responsible for the
development and the regeneration of organ and tissue systems. They are able to renew their …

Intrathecal delivery of autologous culture-expanded adipose tissue-derived mesenchymal
stem cells (AD-MSC) could be utilized to treat traumatic spinal cord injury (SCI). This Phase I …

The potential use of stem cell‐based therapies for the repair and regeneration of various
tissues and organs offers a paradigm shift that may provide alternative therapeutic solutions …

Millions of people lose or damage their organs or tissues due to disease, birth defects, or
accidents each year. Stem cells, such as embryonic stem cells (ESCs), induced pluripotent …

Adult articular cartilage exhibits little capacity for intrinsic repair, and thus even minor injuries
or lesions may lead to progressive damage and osteoarthritic joint degeneration, resulting in …

Mesenchymal stem/stromal cells (MSCs) are promising cell sources for regenerative
therapies due to their multipotency and ready availability, but their application can be …

Facial deformities require precise reconstruction of the appearance and function of the
original tissue. The current standard of care—the use of bone harvested from another region …

Efficient sorting methods are required for the isolation of cellular subpopulations in basic
science and translational applications. Despite this, throughputs, yields, viabilities, and …

Mesenchymal stem cells (MSCs) display substantial cell-to-cell variation. This heterogeneity
manifests among donors, among tissue sources, and within cell populations. Such pervasive …