Blast-related traumatic brain injury: current concepts and research considerations
DW Bryden, JI Tilghman… - Journal of experimental …, 2019 - journals.sagepub.com
Traumatic brain injury (TBI) is a well-known consequence of participation in activities such
as military combat or collision sports. But the wide variability in eliciting circumstances and …
as military combat or collision sports. But the wide variability in eliciting circumstances and …
Integrative neuroinformatics for precision prognostication and personalized therapeutics in moderate and severe traumatic brain injury
Despite changes in guideline-based management of moderate/severe traumatic brain injury
(TBI) over the preceding decades, little impact on mortality and morbidity have been seen …
(TBI) over the preceding decades, little impact on mortality and morbidity have been seen …
Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group
A Olsen, T Babikian, ED Bigler… - Brain imaging and …, 2021 - Springer
The global burden of mortality and morbidity caused by traumatic brain injury (TBI) is
significant, and the heterogeneity of TBI patients and the relatively small sample sizes of …
significant, and the heterogeneity of TBI patients and the relatively small sample sizes of …
Putative survival advantages in young apolipoprotein ɛ4 carriers are associated with increased neural stress
Inheritance of a single copy of the apolipoprotein E (APOE) ɛ4 allele increases risk of
Alzheimer's disease (AD) by 3-4-fold, with homozygosity associated with a 12-16-fold …
Alzheimer's disease (AD) by 3-4-fold, with homozygosity associated with a 12-16-fold …
Broader insights into understanding tumor necrosis factor and neurodegenerative disease pathogenesis infer new therapeutic approaches
Proinflammatory cytokines such as tumor necrosis factor (TNF), with its now appreciated key
roles in neurophysiology as well as neuropathophysiology, are sufficiently well-documented …
roles in neurophysiology as well as neuropathophysiology, are sufficiently well-documented …
History of traumatic brain injury does not alter course of neurocognitive decline in older adults with and without cognitive impairment.
Objective: Traumatic brain injury (TBI) history is associated with dementia risk, but it is
unclear whether TBI history significantly hastens neurocognitive decline in older adults …
unclear whether TBI history significantly hastens neurocognitive decline in older adults …
Genetic insights into Alzheimer's disease
Alzheimer's disease (AD) is a pervasive, relentlessly progressive neurodegenerative
disorder that includes both hereditary and sporadic forms linked by common underlying …
disorder that includes both hereditary and sporadic forms linked by common underlying …
[HTML][HTML] Impact of Apolipoprotein E gene polymorphism during normal and pathological conditions of the brain across the lifespan
D Iacono, GC Feltis - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
The central nervous system (CNS) is the cellular substrate for the integration of complex,
dynamic, constant, and simultaneous interactions among endogenous and exogenous …
dynamic, constant, and simultaneous interactions among endogenous and exogenous …
APOE× BDNF interaction and poorer cognitive outcomes among veterans with mild traumatic brain injury: an exploratory study
AF Ton Loy, JS Adler, VC Merritt… - The Journal of …, 2024 - psychiatryonline.org
Objective: The authors examined the interaction between apolipoprotein E (APOE) ε4 and
brain-derived neurotrophic factor (BDNF) Val66Met alleles on neuropsychological …
brain-derived neurotrophic factor (BDNF) Val66Met alleles on neuropsychological …
Apolipoprotein e (APOE) ε4 genotype influences memory performance following remote traumatic brain injury in US military service members and veterans
The purpose of this study was to examine the association between the apolipoprotein E
(APOE) ε4 allele and neurocognitive functioning following traumatic brain injury (TBI) in …
(APOE) ε4 allele and neurocognitive functioning following traumatic brain injury (TBI) in …