mRNA vaccines in disease prevention and treatment

G Zhang, T Tang, Y Chen, X Huang… - Signal transduction and …, 2023 - nature.com
Abstract mRNA vaccines have emerged as highly effective strategies in the prophylaxis and
treatment of diseases, thanks largely although not totally to their extraordinary performance …

Neo-antigen mRNA vaccines

A Esprit, W de Mey, R Bahadur Shahi, K Thielemans… - Vaccines, 2020 - mdpi.com
The interest in therapeutic cancer vaccines has caught enormous attention in recent years
due to several breakthroughs in cancer research, among which the finding that successful …

[HTML][HTML] The paradigm shift in treatment from Covid-19 to oncology with mRNA vaccines

J Wei, AM Hui - Cancer Treatment Reviews, 2022 - Elsevier
Abstract mRNA vaccines have gained popularity over the last decade as a versatile tool for
develo** novel therapeutics. The recent success of coronavirus disease (COVID-19) …

The tumor microenvironment of epithelial ovarian cancer and its influence on response to immunotherapy

GM Rodriguez, KJC Galpin, CW McCloskey… - Cancers, 2018 - mdpi.com
Immunotherapy as a treatment for cancer is a growing field of endeavor but reports of
success have been limited for epithelial ovarian cancer. Overcoming the challenges to …

mRNA-based dendritic cell vaccines

D Benteyn, C Heirman, A Bonehill… - Expert review of …, 2015 - Taylor & Francis
Cancer immunotherapy has been proposed as a powerful treatment modality. Active
immunotherapy aspires to stimulate the patient's immune system, particularly T cells. These …

Facts and hopes in immunotherapy of endometrial cancer

JA Marín-Jiménez, S García-Mulero, X Matías-Guiu… - Clinical Cancer …, 2022 - AACR
Immunotherapy with checkpoint inhibitors has changed the paradigm of treatment for many
tumors, and endometrial carcinoma is not an exception. Approved treatment options are …

Therapeutic cancer vaccination with ex vivo RNA-transfected dendritic cells—an update

J Dörrie, N Schaft, G Schuler, B Schuler-Thurner - Pharmaceutics, 2020 - mdpi.com
Over the last two decades, dendritic cell (DC) vaccination has been studied extensively as
active immunotherapy in cancer treatment and has been proven safe in all clinical trials both …

Dendritic cell vaccines in ovarian cancer

X Zhang, T He, Y Li, L Chen, H Liu, Y Wu… - Frontiers in …, 2021 - frontiersin.org
Ovarian cancer (OC) is one of the most lethal malignant gynecologic tumors, characterized
by an uncertain presentation and poor outcomes. With or without neoadjuvant …

[HTML][HTML] Targeting dendritic cells through gold nanoparticles: A review on the cellular uptake and subsequent immunological properties

S Ahmad, AA Zamry, HTT Tan, KK Wong, JK Lim… - Molecular …, 2017 - Elsevier
Gold nanoparticles (NPs) have been proposed as a highly potential tool in immunotherapies
due to its advantageous properties including customizable size and shapes, surface …

Dendritic cell vaccines: A promising approach in the fight against ovarian cancer

AA Caro, S Deschoemaeker, L Allonsius… - Cancers, 2022 - mdpi.com
Simple Summary With an overall 5-year survival of only 20% for advanced-stage ovarian
cancer patients, enduring and effective therapies are a highly unmet clinical need. Current …