The structure and topology of α-helical coiled coils

AN Lupas, J Bassler, S Dunin-Horkawicz - Fibrous Proteins: Structures and …, 2017 - Springer
Abstract α-Helical coiled coils constitute one of the most diverse folds yet described. They
range in length over two orders of magnitude; they form rods, segmented ropes, barrels …

Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration

MA Casasanta, CC Yoo, B Udayasuryan… - Science …, 2020 - science.org
Fusobacterium nucleatum is implicated in accelerating colorectal cancer (CRC) and is found
within metastatic CRC cells in patient biopsies. Here, we found that bacterial invasion of …

The MPI bioinformatics Toolkit as an integrative platform for advanced protein sequence and structure analysis

V Alva, SZ Nam, J Söding, AN Lupas - Nucleic acids research, 2016 - academic.oup.com
Abstract The MPI Bioinformatics Toolkit (http://toolkit. tuebingen. mpg. de) is an open,
interactive web service for comprehensive and collaborative protein bioinformatic analysis. It …

Recent advances in the understanding of trimeric autotransporter adhesins

AR Kiessling, A Malik, A Goldman - Medical Microbiology and Immunology, 2020 - Springer
Adhesion is the initial step in the infection process of gram-negative bacteria. It is usually
followed by the formation of biofilms that serve as a hub for further spread of the infection …

Outer Membrane Proteome of Veillonella parvula: A Diderm Firmicute of the Human Microbiome

DI Poppleton, M Duchateau, V Hourdel… - Frontiers in …, 2017 - frontiersin.org
Veillonella parvula is a biofilm-forming commensal found in the lungs, vagina, mouth, and
gastro-intestinal tract of humans, yet it may develop into an opportunistic pathogen …

A novel lytic phage potentially effective for phage therapy against Burkholderia pseudomallei in the tropics

Y Wang, X Li, DAB Dance, H **a, C Chen… - Infectious diseases of …, 2022 - Springer
Background Burkholderia pseudomallei is a tropical pathogen that causes melioidosis. Its
intrinsic drug-resistance is a leading cause of treatment failure, and the few available …

Utilizing Whole Fusobacterium Genomes To Identify, Correct, and Characterize Potential Virulence Protein Families

A Umaña, BE Sanders, CC Yoo… - Journal of …, 2019 - Am Soc Microbiol
Fusobacterium spp. are Gram-negative, anaerobic, opportunistic pathogens involved in
multiple diseases, including a link between the oral pathogen Fusobacterium nucleatum and …

Long-Read Sequencing Reveals Genetic Adaptation of Bartonella Adhesin A Among Different Bartonella henselae Isolates

A Thibau, K Hipp, DJ Vaca, S Chowdhury… - Frontiers in …, 2022 - frontiersin.org
Bartonella henselae is the causative agent of cat scratch disease and other clinical entities
such as endocarditis and bacillary angiomatosis. The life cycle of this pathogen, with …

A Short Peptide of Autotransporter Ata Is a Promising Protective Antigen for Vaccination Against Acinetobacter baumannii

P Sun, X Li, C Pan, Z Liu, J Wu, H Wang… - Frontiers in …, 2022 - frontiersin.org
With the emergence of multidrug-resistant strains, Acinetobacter baumannii infection is
becoming a thorny health problem in hospitals. However, there are no licensed vaccines …

The influence of coalescent microbiotic particles from water and soil on the evolution and spread of antimicrobial resistance

F Baquero, TM Coque, N Guerra-Pinto… - Frontiers in …, 2022 - frontiersin.org
Water and soil contain a multiplicity of particulate material coated with bacterial populations
and communities. Microbiotic particles are any type of small particle (measuring less than 2 …