Current progress on antioxidants incorporating the pyrazole core
VLM Silva, J Elguero, AMS Silva - European journal of medicinal chemistry, 2018 - Elsevier
The search of new antioxidants, as drugs candidates, is an active field of medicinal
chemistry. The synthesis of compounds with antioxidant potential has increased in recent …
chemistry. The synthesis of compounds with antioxidant potential has increased in recent …
Recent advances in synthetic strategies and SAR of thiazolidin-4-one containing molecules in cancer therapeutics
Cancer is one of the life-threatening diseases accountable for millions of demises globally.
The inadequate effectiveness of the existing chemotherapy and its harmful effects has …
The inadequate effectiveness of the existing chemotherapy and its harmful effects has …
Design, Synthesis, Molecular docking, and biological evaluation of novel 2, 3-diaryl-1, 3-thiazolidine-4-one derivatives as potential anti-inflammatory and cytotoxic …
Abstract A new series of 2, 3-diaryl-1, 3thiazolidin-4-one derivatives was designed,
synthesized, and evaluated for their cytotoxicity and COXs inhibitory activities. Among these …
synthesized, and evaluated for their cytotoxicity and COXs inhibitory activities. Among these …
Synthesis of phenazone based carboxamide under thiourea reaction conditions. Molecular and crystal structure, Hirshfeld surface analysis and intermolecular …
Considering the added advantage of active pyrazolone pharmacophore and phenazone
drug itself with associated medicinal applications, we herein aim to derivatize this potent …
drug itself with associated medicinal applications, we herein aim to derivatize this potent …
Synthesis of new pyrazolo [3, 4‐d] pyrimidine derivatives and evaluation of their anti‐inflammatory and anticancer activities
HA Abd El Razik, M Mroueh, WH Faour… - Chemical biology & …, 2017 - Wiley Online Library
This study reports the synthesis of two series of new purine bioisosteres comprising a
pyrazolo [3, 4‐d] pyrimidine scaffold linked to piperazine moiety through different amide …
pyrazolo [3, 4‐d] pyrimidine scaffold linked to piperazine moiety through different amide …
Synthesis and biological evaluation of new 1,3-thiazolidine-4-one derivatives of nitro-l-arginine methyl ester
Background l-Arginine is a semi-essential aminoacid with important role in regulation of
physiological processes in humans. It serves as precursor for the synthesis of proteins and is …
physiological processes in humans. It serves as precursor for the synthesis of proteins and is …
Synthesis of novel pyrazolines, their boron–fluorine complexes, and investigation of antibacterial, antioxidant, and enzyme inhibition activities
New 3, 5‐disubstituted‐2‐pyrazoline derivatives (4–6), their boron‐fluorine complexes
(boron (3‐(2′‐aminophenyl), 5‐(2′‐/3′‐/4′‐pyridyl) pyrazoline, BOAPPY)(7–9) and …
(boron (3‐(2′‐aminophenyl), 5‐(2′‐/3′‐/4′‐pyridyl) pyrazoline, BOAPPY)(7–9) and …
Synthesis, Spectroscopic characterization and bactericidal valuation of some metal (II) complexes with new Tridentate Heterocyclic Azo Ligand Type (NNO) Donor
GF Hameed, F Wadday, MAA Farhan… - Egyptian Journal of …, 2021 - journals.ekb.eg
In this article, a synthesized ligand [(1-phenyl-2-pyrazolin-5-one) azo (6-bromo-2-
hydroxynaphthalen-1-yl)] has employed for preparing three new complexes of Co (II), Ni (II) …
hydroxynaphthalen-1-yl)] has employed for preparing three new complexes of Co (II), Ni (II) …
Environmentally benign synthesis of 4-thiazolidinone derivatives using a Co/Al hydrotalcite as heterogeneous catalyst
DD Subhedar, PA Yadav, SR Pawar, BM Bhanage - Catalysis Letters, 2021 - Springer
The present effort describes facile and environmentally benign synthesis of 4-thiazolidinone
via oxidative cyclocondensation of benzyl alcohols, various substituted aromatic anilines …
via oxidative cyclocondensation of benzyl alcohols, various substituted aromatic anilines …
[PDF][PDF] Assessment of in vitro antioxidant and anti-inflammatory activities of new azetidin-2-one derivatives of ferulic acid
The in vitro antioxidant potential of new azetidin-2-one derivatives of ferulic acid was
evaluated according to DPPH and ABTS.+ radicals scavenging assays. Their anti …
evaluated according to DPPH and ABTS.+ radicals scavenging assays. Their anti …