Noncoding RNA: RNA regulatory networks in cancer

JJ Chan, Y Tay - International journal of molecular sciences, 2018‏ - mdpi.com
Noncoding RNAs (ncRNAs) constitute the majority of the human transcribed genome. This
largest class of RNA transcripts plays diverse roles in a multitude of cellular processes, and …

Coding, or non-coding, that is the question

L Poliseno, M Lanza, PP Pandolfi - Cell Research, 2024‏ - nature.com
The advent of high-throughput sequencing uncovered that our genome is pervasively
transcribed into RNAs that are seemingly not translated into proteins. It was also found that …

Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer

J Chen, Y Yu, H Li, Q Hu, X Chen, Y He, C Xue, F Ren… - Molecular cancer, 2019‏ - Springer
Background The long non-coding RNA PVT1 (lncRNA PVT1) has been reported to act as an
oncogenic regulator of several cancers. However, its expression and function in gallbladder …

Long noncoding RNAs in cancer: from discovery to therapeutic targets

R Choudhari, MJ Sedano, AL Harrison… - Advances in clinical …, 2020‏ - Elsevier
Long noncoding RNAs (lncRNAs) have recently gained considerable attention as key
players in biological regulation; however, the mechanisms by which lncRNAs govern …

Long noncoding RNA CRNDE promotes multiple myeloma cell growth by suppressing miR-451

YB Meng, X He, YF Huang, QN Wu… - Oncology …, 2017‏ - pmc.ncbi.nlm.nih.gov
It has been determined that long noncoding RNAs (lncRNAs) are identified as a potential
regulatory factor in multiple tumors as well as multiple myeloma (MM). However, the role of …

Interactions between short and long noncoding RNAs

I Ulitsky - FEBS letters, 2018‏ - Wiley Online Library
It is now evident that noncoding RNAs play key roles in regulatory networks determining cell
fate and behavior, in a myriad of different conditions, and across all species. Among these …

[HTML][HTML] Identification of the 3-lncRNA signature as a prognostic biomarker for colorectal cancer

S Liu, Q Cao, G An, B Yan, L Lei - International journal of molecular …, 2020‏ - mdpi.com
Colorectal cancer (CRC) is one of the most common malignant carcinomas in the world, and
metastasis is the main cause of CRC-related death. However, the molecular network …

The role of lncRNAs in the distant metastasis of breast cancer

Y Wu, A Shao, L Wang, K Hu, C Yu, C Pan… - Frontiers in …, 2019‏ - frontiersin.org
Breast cancer (BC) remains the most frequently diagnosed cancer worldwide. Among breast
cancer patients, distant metastasis and invasion is the leading cause of BC related death …

RETRACTED: The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis

C Yang, J Zheng, Y Xue, H Yu, X Liu, J Ma… - Frontiers in Molecular …, 2018‏ - frontiersin.org
Glioblastoma (GBM) is the most aggressive and malignant primary tumor. Angiogenesis
plays a critical role in the progression of GBM. Previous studies have indicated that long non …

The implications of ncRNAs in the development of human diseases

E López-Jiménez, E Andrés-León - Non-coding RNA, 2021‏ - mdpi.com
The mammalian genome comprehends a small minority of genes that encode for proteins
(barely 2% of the total genome in humans) and an immense majority of genes that are …