High mutation rates limit evolutionary adaptation in Escherichia coli

K Sprouffske, J Aguilar-Rodriguez, P Sniegowski… - PLoS …, 2018 - journals.plos.org
Mutation is fundamental to evolution, because it generates the genetic variation on which
selection can act. In nature, genetic changes often increase the mutation rate in systems that …

Genomics of Diversification of Pseudomonas aeruginosa in Cystic Fibrosis Lung-like Conditions

A Schick, S Shewaramani… - Genome biology and …, 2022 - academic.oup.com
Pseudomonas aeruginosa is among the most problematic opportunistic pathogens for adults
with cystic fibrosis (CF), causing repeated and resilient infections in the lung and …

Emerging Adaptive Strategies Under Temperature Fluctuations in a Laboratory Evolution Experiment of Escherichia Coli

M Lambros, X Pechuan-Jorge, D Biro, K Ye… - Frontiers in …, 2021 - frontiersin.org
Generalists and specialists are types of strategies individuals can employ that can evolve in
fluctuating environments depending on the extremity and periodicity of the fluctuation. To …

Comparison of E. coli based self-inducible expression systems containing different human heat shock proteins

FS Shariati, M Keramati, V Valizadeh, RA Cohan… - Scientific Reports, 2021 - nature.com
IPTG-inducible promoter is popularly used for the expression of recombinant proteins.
However, it is not suitable at the industrial scale due to the high cost and toxicity on the …

Antimicrobial susceptibility and integrons detection among extended-spectrum β-lactamase producing Enterobacteriaceae isolates in patients with urinary tract …

KT Abubaker, KA Anwar - PeerJ, 2023 - peerj.com
Background Integrons are bacterial mobile genetic components responsible for mediating
the antibiotic resistance process by carrying and spreading antimicrobial resistance genes …

Consequences of Cryopreservation in Diverse Natural Isolates of Saccharomyces cerevisiae

KM Wing, MA Phillips, AR Baker… - Genome Biology and …, 2020 - academic.oup.com
Experimental evolution allows the observation of change over time as laboratory
populations evolve in response to novel, controlled environments. Microbial evolution …

Experimental evolution of phytoplankton fatty acid thermal reaction norms

DR O'Donnell, Z Du, E Litchman - Evolutionary applications, 2019 - Wiley Online Library
Temperature effects on the fatty acid (FA) profiles of phytoplankton, major primary producers
in the ocean, have been widely studied due to their importance as industrial feedstocks and …

CRISPR-Cas9-mediated barcode insertion into Bacillus thuringiensis for surrogate tracking

SA Higgins, F Kara Murdoch, JM Clifton… - Microbiology …, 2024 - journals.asm.org
The use of surrogate organisms can enable researchers to safely conduct research on
pathogens and in a broader set of conditions. Being able to differentiate between the …

Improving the practicality of recombinant Escherichia coli biosensor in detecting trace Cr(VI) by modifying the cryogenic storage conditions of biosensors and …

GH Wang, CH Tang, CY Cheng… - Journal of Environmental …, 2023 - Taylor & Francis
Abstract Hexavalent chromium (Cr (VI)) is a global environmental pollutant. To reduce the
risk caused by Cr (VI), a simple, accurate, reproducible, and inexpensive method for …

Genome wide assessment of genetic diversity and transcript variations in 17 accessions of the model diatom Phaeodactylum tricornutum

C Timothée, F Yang, E Manirakiza, O Ait-Mohamed… - bioRxiv, 2023 - biorxiv.org
Diatoms, a prominent group of phytoplankton, have a significant impact on both the oceanic
food chain and carbon sequestration, thereby playing a crucial role in regulating the climate …