The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …

Nanotechnology has shown tremendous success in the drug delivery field for more effective
and safer therapy, and has recently enabled the clinical approval of RNA medicine, a new …

How soft corona, the protein corona's outer layer, contributes to biological identity of
nanomaterials is largely because capturing protein composition of the soft corona in situ …

The blood circulation is considered the only way for the orally administered nanoparticles to
enter the central nervous systems (CNS), whereas non-blood route-mediated nanoparticle …

Upon entering the biological milieu, nanomedicines swiftly interact with the surrounding
tissue fluid, subsequently being enveloped by a dynamic interplay of biomacromolecules …

A biomolecular coating, or biocorona, forms on the surface of engineered nanomaterials
(ENMs) immediately as they enter biological or environmental systems, defining their …

Although a wide variety of nanoparticles (NPs) have been engineered for use as disease
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …

Extravasation is the first step for nanomedicines in circulation to reach targeted solid tumors.
Traditional nanomedicines have been designed to extravasate into tumor interstitium …

Ferroptosis, a completely new form of regulated cell death, is mainly caused by an
imbalance between oxidative damage and reductive protection and has shown great anti …

The dynamic protein corona formed on nanocarriers has been revealed to strongly affect
their in vivo behaviors. Precisely manipulating the formation of protein corona on …