Historically, the mammalian brain was thought to lack stem cells as no new neurons were
found to be made in adulthood. That dogma changed∼ 25 years ago with the identification …

The cerebral cortex develops through a carefully conscripted series of cellular and
molecular events that culminate in the production of highly specialized neuronal and glial …

The inner ear, projections, and brainstem nuclei are essential components of the auditory
and vestibular systems. It is believed that the evolution of complex systems depends on …

Asymmetric neuronal expansion is thought to drive evolutionary transitions between
lissencephalic and gyrencephalic cerebral cortices. We report that Neurog2 and Ascl1 …

The human brain's complex morphology is spatially constrained by numerous intrinsic and
extrinsic physical interactions. Spatial constraints help to identify the source of …

Intrauterine growth restriction (IUGR) affects~ 10% of human pregnancies, results in infants
born small for gestational age (SGA), and is associated with motor and cognitive deficits …

Colon adenocarcinoma (COAD) accounts for 95% of colon cancer cases, with the 5-year
survival rate significantly affected by local or distant metastases. Yiqi Jianpi Huayu Jiedu …

Polymicrogyria (PMG) is a relatively common complex malformation with cortical
development, characterized by an exorbitant number of abnormally tiny gyri separated by …

Abstract Development of the nervous system depends on signaling centers–specialized
cellular populations that produce secreted molecules to regulate neurogenesis in the …

The mammalian cerebral cortex has changed significantly during evolution. As a result of the
increase in the number of neurons and glial cells in the cerebral cortex, its size has markedly …