Adipokines in inflammation and metabolic disease

N Ouchi, JL Parker, JJ Lugus, K Walsh - Nature reviews immunology, 2011 - nature.com
The worldwide epidemic of obesity has brought considerable attention to research aimed at
understanding the biology of adipocytes (fat cells) and the events occurring in adipose …

Role of leptin in inflammation and vice versa

A Pérez-Pérez, F Sánchez-Jiménez… - International journal of …, 2020 - mdpi.com
Inflammation is an essential immune response for the maintenance of tissue homeostasis. In
a general sense, acute and chronic inflammation are different types of adaptive response …

Leptin in the interplay of inflammation, metabolism and immune system disorders

V Abella, M Scotece, J Conde, J Pino… - Nature Reviews …, 2017 - nature.com
Leptin is one of the most relevant factors secreted by adipose tissue and the forerunner of a
class of molecules collectively called adipokines. Initially discovered in 1994, its crucial role …

The complex role of adipokines in obesity, inflammation, and autoimmunity

EB Taylor - Clinical Science, 2021 - portlandpress.com
The global obesity epidemic is a major contributor to chronic disease and disability in the
world today. Since the discovery of leptin in 1994, a multitude of studies have characterized …

Obesity, fat mass and immune system: role for leptin

V Francisco, J Pino, V Campos-Cabaleiro… - Frontiers in …, 2018 - frontiersin.org
Obesity is an epidemic disease characterized by chronic low-grade inflammation associated
with a dysfunctional fat mass. Adipose tissue is now considered an extremely active …

[HTML][HTML] Adipokines: a link between obesity and cardiovascular disease

K Nakamura, JJ Fuster, K Walsh - Journal of cardiology, 2014 - Elsevier
Obesity is a risk factor for various cardiovascular diseases including hypertension,
atherosclerosis, and myocardial infarction. Recent studies aimed at understanding the …

Malnutrition and infection: complex mechanisms and global impacts

UE Schaible, SHE Kaufmann - PLoS medicine, 2007 - journals.plos.org
Malnutrition and Infection: Complex Mechanisms and Global Impacts | PLOS Medicine Skip to
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Obesity and infection

ME Falagas, M Kompoti - The Lancet infectious diseases, 2006 - thelancet.com
Obesity increases morbidity and mortality through its multiple effects on nearly every human
system. However, the various aspects of the association between obesity and infection have …

The weight of leptin in immunity

AL Cava, G Matarese - Nature Reviews Immunology, 2004 - nature.com
Leptin is an adipocyte-derived hormone/cytokine that links nutritional status with
neuroendocrine and immune functions. As a hormone, leptin regulates food intake and …

The role of exercise in the interplay between myokines, hepatokines, osteokines, adipokines, and modulation of inflammation for energy substrate redistribution and …

AM Gonzalez-Gil, L Elizondo-Montemayor - Nutrients, 2020 - mdpi.com
Exercise is an effective strategy for preventing and treating obesity and its related
cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue …