This study was focused on exploring the role of the HIV-1 Tat protein in mediating microglial
ferroptosis. Exposure of mouse primary microglial cells (mPMs) to HIV-1 Tat protein resulted …

Recent studies indicated that hepatocyte senescence plays an important role in the
development of alcoholic fatty liver disease (AFLD), suggesting that inhibition of hepatocyte …

Oxylipins are active lipid compounds formed through the oxidation of unsaturated fatty acids.
These compounds have drawn considerable attention due to the potential impact on human …

Consumption of alcohol has widespread effects on the human body. The organs that are
most significantly impacted are the liver and digestive system. When alcohol is consumed, it …

Numerous studies have shown that 1-oleate-2-palmitate-3-linoleate (OPL) is the most
abundant TAG in Chinese human milk, which is significantly different from human milk in …

Alcoholic liver disease is highly prevalent but poorly identified and characterized, leading to
knowledge gaps, which impairs early diagnosis. Excessive alcohol consumption is known to …

Despite the high prevalence of alcoholic liver disease, its identification and characterization
remain poor, especially in early stages such as alcoholic fatty liver disease and alcoholic …

Given the inevitable human exposure owing to its increasing production and utilization, the
comprehensive safety evaluation of silica nanoparticles (SiNPs) has sparked concerns …

Oxidized lipids have been well known as potential markers of oxidative stress or other
disorders in physiological/pathological processes, such as cardiovascular diseases …

In recent years, there have been significant advances in pathological research on alcoholic
liver disease (ALD), with suitable animal models making a significant contribution. However …