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Fluorescent Probes and Quenchers in Studies of Protein Folding and Protein‐Lipid Interactions
Fluorescence spectroscopy provides numerous methodological tools for structural and
functional studies of biological macromolecules and their complexes. All fluorescence …
functional studies of biological macromolecules and their complexes. All fluorescence …
Opportunities and challenges of fatty acid conjugated therapeutics
Instability, poor cellular uptake and unfavorable pharmacokinetics and biodistribution of
many therapeutic molecules require modification in their physicochemical properties. The …
many therapeutic molecules require modification in their physicochemical properties. The …
From haemadin to haemanorm: Synthesis and characterization of full‐length haemadin from the leech Haemadipsa sylvestris and of a novel bivalent, highly potent …
Hirudin from Hirudo medicinalis is a bivalent α‐Thrombin (αT) inhibitor, targeting the enzyme
active site and exosite‐I, and is currently used in anticoagulant therapy along with its …
active site and exosite‐I, and is currently used in anticoagulant therapy along with its …
Indolizinylalanine Regioisomers: Tryptophan Isosteres with Bathochromic Fluorescence Emission
GID Cooper, I Saha, J Newman, RH Shin… - The Journal of …, 2024 - ACS Publications
We have developed a high yielding synthesis of indolizine and directly elaborated the
molecule into three optically active indolizinylalanine regioisomers. The protocols exploit …
molecule into three optically active indolizinylalanine regioisomers. The protocols exploit …
[HTML][HTML] A conserved Neurite Outgrowth and Guidance motif with biomimetic potential in neuronal Cell Adhesion Molecules
The discovery of conserved protein motifs can, in turn, unveil important regulatory signals,
and when properly designed, synthetic peptides derived from such motifs can be used as …
and when properly designed, synthetic peptides derived from such motifs can be used as …
Development and study of aminocatalyzed asymmetric organic reactions
JM de Carvalho Marques Dourado - 2021 - mspace.lib.umanitoba.ca
Chirality is an important feature that many Organic molecules possess and can have huge
repercussions in the activity of Organic compounds. Therefore, the development of …
repercussions in the activity of Organic compounds. Therefore, the development of …