Biological activity of dihydropyrimidinone (DHPM) derivatives: A systematic review

LHS Matos, FT Masson, LA Simeoni… - European journal of …, 2018 - Elsevier
Dihydropyrimidinones are heterocycles with a pyrimidine moiety in the ring nucleus, which,
in recent decades, have aroused interest in medicinal chemistry due to alleged versatile …

[HTML][HTML] Greener organic synthetic methods: Sonochemistry and heterogeneous catalysis promoted multicomponent reactions

IV Machado, JRN Dos Santos, MAP Januario… - Ultrasonics …, 2021 - Elsevier
Ultrasound is an essential technique to improve organic synthesis from the point of view of
green chemistry, as it can promote better yields and selectivities, in addition to shorter …

Synthesis and biological activity of pyrimidines-containing hybrids: Focusing on pharmacological application

E Zarenezhad, M Farjam, A Iraji - Journal of Molecular Structure, 2021 - Elsevier
Heterocyclic derivatives as a major group of organic compounds are enormously used for a
wide range of pharmaceutical and industrial applications. They are known for their biological …

[HTML][HTML] A mini-review on Biginelli adducts with notable pharmacological properties

 de Fátima, TC Braga, LS Neto, BS Terra… - Journal of advanced …, 2015 - Elsevier
Since the disclosure of Biginelli reaction by the chemist Pietro Biginelli, functionalized 3, 4-
dihydropyrimidin-2 (1H)-ones/thiones (DHPMs) have emerged as prototypes for the design …

Biginelli reaction mediated synthesis of antimicrobial pyrimidine derivatives and their therapeutic properties

M Marinescu - Molecules, 2021 - mdpi.com
Antimicrobial resistance was one of the top priorities for global public health before the start
of the 2019 coronavirus pandemic (COVID-19). Moreover, in this changing medical …

The Biginelli reaction is a urea-catalyzed organocatalytic multicomponent reaction

M Puripat, R Ramozzi, M Hatanaka… - The Journal of …, 2015 - ACS Publications
The recently developed artificial force induced reaction (AFIR) method was applied to
search systematically all possible multicomponent pathways for the Biginelli reaction …

Bioinspired synergistic formulation from dihydropyrimdinones and iodide ions for corrosion inhibition of carbon steel in sulphuric acid

P Singh, DS Chauhan, SS Chauhan, G Singh… - Journal of Molecular …, 2020 - Elsevier
The adsorption and corrosion inhibition behavior of three dihydropyrimidinone (DHPM)
derivatives on carbon steel in 0.5 M sulphuric acid solution is investigated in the present …

Caralluma europaea (Guss.) NEBr.: Anti-Inflammatory, Antifungal, and Antibacterial Activities against Nosocomial Antibiotic-Resistant Microbes of Chemically …

FEZ Amrati, M Bourhia, H Saghrouchni, M Slighoua… - Molecules, 2021 - mdpi.com
Caralluma europaea (Guss.) NE Br.:(C. europaea) is a wild medicinal plant belonging to the
family Apocynaceae. It is commonly used in traditional medicines for treating several …

Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal …

S Manzoor, SK Prajapati, S Majumdar, MK Raza… - European Journal of …, 2021 - Elsevier
Alzheimer's disease (AD) is multifactorial, progressive neurodegeneration with impaired
behavioural and cognitive functions. The multitarget-directed ligand (MTDL) strategies are …

Advances in Biginelli reaction: A comprehensive review

A Chandravarkar, T Aneeja… - Journal of Heterocyclic …, 2024 - Wiley Online Library
The Biginelli reaction, a conventional three‐component reaction provides 3, 4‐
dihydropyrimidin‐2 (1H)‐ones/thiones via one‐pot acid catalyzed cyclocondensation of an …