More than a 'speed gene': ACTN3 R577X genotype, trainability, muscle damage, and the risk for injuries

J Del Coso, D Hiam, P Houweling, LM Pérez… - European journal of …, 2019 - Springer
A common null polymorphism (rs1815739; R577X) in the gene that codes for α-actinin-3
(ACTN3) has been related to different aspects of exercise performance. Individuals who are …

Genetic influences in sport and physical performance

Z Puthucheary, JRA Skipworth, J Rawal, M Loosemore… - Sports medicine, 2011 - Springer
The common inheritance of approximately 20 000 genes defines each of us as human.
However, substantial variation exists between individual human genomes, including …

ACTN3 genotype, athletic status, and life course physical capability: meta‐analysis of the published literature and findings from nine studies

T Alfred, Y Ben‐Shlomo, R Cooper, R Hardy… - Human …, 2011 - Wiley Online Library
Abstract The ACTN3 R577X (rs1815739) genotype has been associated with athletic status
and muscle phenotypes, although not consistently. Our objective was to conduct a meta …

[PDF][PDF] Advances in exercise, fitness, and performance genomics

T Rankinen, SM Roth, MS Bray, R Loos… - Medicine & Science …, 2010 - paulogentil.com
Advances in Exercise, Fitness, and Performance Genomics Page 1 by the American College of
Sports Medicine. Unauthorized reproduction of this article is prohibited. Copyright @ 2010 …

Effect of ACTN3 gene on strength and endurance in soccer players

EM Pimenta, DB Coelho, CE Veneroso… - The Journal of …, 2013 - journals.lww.com
Abstract Pimenta, EM, Coelho, DB, Veneroso, CE, Barros Coelho, EJ, Cruz, IR, Morandi, RF,
De A. Pussieldi, G, Carvalho, MRS, Garcia, ES, and De Paz Fernández, JA. Effect of ACTN3 …

Is evolutionary loss our gain? The role of ACTN3 p.Arg577Ter (R577X) genotype in athletic performance, ageing, and disease

PJ Houweling, ID Papadimitriou, JT Seto… - Human …, 2018 - Wiley Online Library
A common null polymorphism in the ACTN3 gene (rs1815739: C> T) results in replacement
of an arginine (R) with a premature stop codon (X) at amino acid 577 in the fast muscle …

Association analysis of ACE and ACTN3 in elite Caucasian and East Asian swimmers

G Wang, E Mikami, LL Chiu… - … and science in …, 2013 - researchonline.ljmu.ac.uk
Purpose: Polymorphic variation in the angiotensin-converting enzyme (ACE) and α-actinin-3
(ACTN3) genes has been reported to be associated with endurance and/or power-related …

Association of the ACTN3 R577X (rs1815739) polymorphism with elite power sports: A meta-analysis

P Tharabenjasin, N Pabalan, H Jarjanazi - PLoS One, 2019 - journals.plos.org
Objective The special status accorded to elite athletes stems from their uncommon genetic
potential to excel in world-class power sports (PS). Genetic polymorphisms have been …

Muscle Work and Its Relationship with ACE and ACTN3 Polymorphisms Are Associated with the Improvement of Explosive Strength

A Melián Ortiz, S Laguarta-Val, D Varillas-Delgado - Genes, 2021 - mdpi.com
Background: The potential influence of genetics in athletic performance allows the search for
genetic profiles associated with muscular work for the orientation of strength training and …

ACTN3 R577X genotype is associated with sprinting in elite Japanese athletes

E Mikami, N Fuku, H Murakami… - … journal of sports …, 2014 - thieme-connect.com
The ACTN3 R577X genotype has been found to associate with sprint/power phenotypes in
all elite athlete cohorts investigated. This association has not been extensively studied in …