Applications of genoty** by sequencing in aquaculture breeding and genetics

D Robledo, C Palaiokostas, L Bargelloni… - Reviews in …, 2018 - Wiley Online Library
Selective breeding is increasingly recognized as a key component of sustainable production
of aquaculture species. The uptake of genomic technology in aquaculture breeding has …

Association map** in plants in the post-GWAS genomics era

PK Gupta, PL Kulwal, V Jaiswal - Advances in genetics, 2019 - Elsevier
With the availability of DNA-based molecular markers during early 1980s and that of
sophisticated statistical tools in late 1980s and later, it became possible to identify genomic …

The Korea Biobank Array: design and identification of coding variants associated with blood biochemical traits

S Moon, YJ Kim, S Han, MY Hwang, DM Shin… - Scientific reports, 2019 - nature.com
We introduce the design and implementation of a new array, the Korea Biobank Array
(referred to as KoreanChip), optimized for the Korean population and demonstrate findings …

GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy

L Broer, AS Buchman, J Deelen… - … Series A: Biomedical …, 2015 - academic.oup.com
Background. The genetic contribution to longevity in humans has been estimated to range
from 15% to 25%. Only two genes, APOE and FOXO3, have shown association with …

Towards the identification of the loci of adaptive evolution

C Pardo‐Diaz, C Salazar… - Methods in Ecology and …, 2015 - Wiley Online Library
Establishing the genetic and molecular basis underlying adaptive traits is one of the major
goals of evolutionary geneticists in order to understand the connection between genotype …

Inheritance of somatic mutations by animal offspring

KL Vasquez Kuntz, SA Kitchen, TL Conn… - Science …, 2022 - science.org
Since 1892, it has been widely assumed that somatic mutations are evolutionarily irrelevant
in animals because they cannot be inherited by offspring. However, some nonbilaterians …

Revisiting inconsistency in large pharmacogenomic studies

Z Safikhani, P Smirnov, M Freeman… - …, 2017 - pmc.ncbi.nlm.nih.gov
In 2013, we published a comparative analysis of mutation and gene expression profiles and
drug sensitivity measurements for 15 drugs characterized in the 471 cancer cell lines …

Forensic investigation approaches of searching relatives in DNA databases

J Ge, B Budowle - Journal of Forensic Sciences, 2021 - Wiley Online Library
There are several indirect database searching approaches to identify the potential source of
a forensic biological sample. These DNA‐based approaches are familial searching, Y‐STR …

Similarities and differences between variants called with human reference genome HG19 or HG38

B Pan, R Kusko, W **ao, Y Zheng, Z Liu, C **ao… - BMC …, 2019 - Springer
Background Reference genome selection is a prerequisite for successful analysis of next
generation sequencing (NGS) data. Current practice employs one of the two most recent …

Drug repositioning through network pharmacology

H Ye, J Wei, K Tang, R Feuers… - Current topics in …, 2016 - ingentaconnect.com
Low drug productivity has been a significant problem of the pharmaceutical industry for
several decades even though numerous novel technologies were introduced during this …