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Signaling pathways in vascular function and hypertension: molecular mechanisms and therapeutic interventions
J Ma, Y Li, X Yang, K Liu, X Zhang, X Zuo… - Signal transduction and …, 2023 - nature.com
Hypertension is a global public health issue and the leading cause of premature death in
humans. Despite more than a century of research, hypertension remains difficult to cure due …
humans. Despite more than a century of research, hypertension remains difficult to cure due …
[HTML][HTML] Gut microbiota in hypertension and atherosclerosis: a review
Gut microbiota and its metabolites such as short chain fatty acids (SCFA),
lipopolysaccharides (LPS), and trimethylamine-N-oxide (TMAO) impact cardiovascular …
lipopolysaccharides (LPS), and trimethylamine-N-oxide (TMAO) impact cardiovascular …
The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease
T Yang, EM Richards, CJ Pepine… - Nature Reviews …, 2018 - nature.com
Crosstalk between the gut microbiota and the host has attracted considerable attention
owing to its involvement in diverse diseases. Chronic kidney disease (CKD) is commonly …
owing to its involvement in diverse diseases. Chronic kidney disease (CKD) is commonly …
Gut dysbiosis is linked to hypertension
Emerging evidence suggests that gut microbiota is critical in the maintenance of
physiological homeostasis. This study was designed to test the hypothesis that dysbiosis in …
physiological homeostasis. This study was designed to test the hypothesis that dysbiosis in …
Hypertension-linked pathophysiological alterations in the gut
Rationale: Sympathetic nervous system control of inflammation plays a central role in
hypertension. The gut receives significant sympathetic innervation, is densely populated …
hypertension. The gut receives significant sympathetic innervation, is densely populated …
Aging, arterial stiffness, and hypertension
Z Sun - Hypertension, 2015 - ahajournals.org
Arterial stiffening, at least, reflects gradual fragmentation and loss of elastin fibers and
accumulation of stiffer collagen fibers in the media of large arteries and occurs …
accumulation of stiffer collagen fibers in the media of large arteries and occurs …
Gut microbiome and neuroinflammation in hypertension
EM Richards, J Li, BR Stevens, CJ Pepine… - Circulation …, 2022 - ahajournals.org
Hypertension is a worldwide problem with major impacts on health including morbidity and
mortality, as well as consumption of health care resources. Nearly 50% of American adults …
mortality, as well as consumption of health care resources. Nearly 50% of American adults …
Critical role of the interaction gut microbiota–sympathetic nervous system in the regulation of blood pressure
Association between gut dysbiosis and neurogenic diseases, such as hypertension, has
been described. The aim of this study was to investigate whether changes in the gut …
been described. The aim of this study was to investigate whether changes in the gut …
[HTML][HTML] Gut microbiota-derived short-chain fatty acids and hypertension: Mechanism and treatment
F Yang, H Chen, Y Gao, N An, X Li, X Pan… - Biomedicine & …, 2020 - Elsevier
Hypertension (HTN) is an growing emerging health issue around across the world. In recent
years, increasing attention has been paid to the role of dysbacteriosis in HTN and its …
years, increasing attention has been paid to the role of dysbacteriosis in HTN and its …
Impaired autonomic nervous system-microbiome circuit in hypertension: a premise for hypertension therapy
Hypertension affects an estimated 103 million Americans, yet gaps in knowledge continue to
limit its successful management. Rapidly emerging evidence is linking gut dysbiosis to many …
limit its successful management. Rapidly emerging evidence is linking gut dysbiosis to many …