Organic cation transporters in health and disease
H Koepsell, LC Daws - Pharmacological reviews, 2020 - Elsevier
The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2,
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …
The biology of ergothioneine, an antioxidant nutraceutical
Ergothioneine (ERG) is an unusual thio-histidine betaine amino acid that has potent
antioxidant activities. It is synthesised by a variety of microbes, especially fungi (including in …
antioxidant activities. It is synthesised by a variety of microbes, especially fungi (including in …
[HTML][HTML] Solute carrier transporters: the metabolic gatekeepers of immune cells
Solute carrier (SLC) transporters meditate many essential physiological functions, including
nutrient uptake, ion influx/efflux, and waste disposal. In its protective role against tumors and …
nutrient uptake, ion influx/efflux, and waste disposal. In its protective role against tumors and …
The microbiota in inflammatory bowel disease
D Sheehan, C Moran, F Shanahan - Journal of gastroenterology, 2015 - Springer
This review explores our current understanding of the complex interaction between
environmental risk factors, genetic traits and the development of inflammatory bowel …
environmental risk factors, genetic traits and the development of inflammatory bowel …
Alterations in intestinal permeability
The goal of this review is to describe barrier function of the intestine, the structure of the tight
junction, methods to evaluate intestinal permeability, and most importantly the relevance of …
junction, methods to evaluate intestinal permeability, and most importantly the relevance of …
[HTML][HTML] Ergothioneine; antioxidant potential, physiological function and role in disease
Since its discovery, the unique properties of the naturally occurring amino acid, L-
ergothioneine (EGT; 2-mercaptohistidine trimethylbetaine), have intrigued researchers for …
ergothioneine (EGT; 2-mercaptohistidine trimethylbetaine), have intrigued researchers for …
The Bacillus subtilis quorum-sensing molecule CSF contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter
Bacteria use quorum-sensing molecules (QSMs) to communicate within as well as across
species. However, the effects of QSMs on eukaryotic host cells have received limited …
species. However, the effects of QSMs on eukaryotic host cells have received limited …
Biochemical and Structural Characterization of OvoATh2: A Mononuclear Nonheme Iron Enzyme from Hydrogenimonas thermophila for Ovothiol Biosynthesis
X Wang, S Hu, J Wang, T Zhang, K Ye, A Wen… - ACS …, 2023 - ACS Publications
Ovothiol A and ergothioneine are thiol-histidine derivatives with sulfur substitutions at the δ-
carbon or ε-carbon of the l-histidine imidazole ring, respectively. Both ovothiol A and …
carbon or ε-carbon of the l-histidine imidazole ring, respectively. Both ovothiol A and …
Ergothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis
Ergothioneine (ET) is a diet-derived, thiolated derivative of histidine with antioxidant
properties. Although ET is produced only by certain fungi and bacteria, it can be found at …
properties. Although ET is produced only by certain fungi and bacteria, it can be found at …
Cyanobacteria produce high levels of ergothioneine
C Pfeiffer, T Bauer, B Surek, E Schömig… - Food Chemistry, 2011 - Elsevier
Ergothioneine (ET) is a unique natural antioxidant. We have examined the origin of ET in
zebrafish. There was virtually no ET, measured by LC–MS, in most tank vegetation (plant …
zebrafish. There was virtually no ET, measured by LC–MS, in most tank vegetation (plant …