Life expectancy is increasing worldwide, with a resultant increase in the elderly population.
Aging is characterized by the progressive loss of skeletal muscle mass and strength–a …

Flow-mediated dilation (FMD) is a noninvasive index of endothelial function and vascular
health in humans. Studies examining the role of nitric oxide (NO) are not conclusive. In this …

The introduction of duplex Doppler ultrasound almost half a century ago signified a
revolutionary advance in the ability to assess limb blood flow in humans. It is now widely …

During exercise, oxygen delivery to skeletal muscle is elevated to meet the increased
oxygen demand. The increase in blood flow to skeletal muscle is achieved by vasodilators …

To determine whether conditions for O2 utilization and O2 off-loading from the hemoglobin
are different in exercising arms and legs, six cross-country skiers participated in this study …

Flow‐mediated dilatation (FMD) of the brachial and radial arteries is an important research
tool for assessment of endothelial function in vivo, and is nitric oxide (NO) dependent. The …

To determine central and peripheral hemodynamic responses to upright leg cycling
exercise, nine physically active men underwent measurements of arterial blood pressure …

Aging appears to attenuate leg blood flow during exercise; in contrast, such data are scant
and do not support this contention in the arm. Therefore, to determine whether aging has …

Previous investigations of age-associated changes in flow-mediated vasodilation (FMD) in
women have been limited to the upper extremity and have not accounted for possible age …

Contracting skeletal muscle can overcome sympathetic vasoconstrictor activity (functional
sympatholysis), which allows for a blood supply that matches the metabolic demand. This …