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[HTML][HTML] Stress and telomere shortening: Insights from cellular mechanisms
Short telomeres confer risk of degenerative diseases. Chronic psychological stress can lead
to disease through many pathways, and research from in vitro studies to human longitudinal …
to disease through many pathways, and research from in vitro studies to human longitudinal …
COPD and multimorbidity: recognising and addressing a syndemic occurrence
Most patients with chronic obstructive pulmonary disease (COPD) have at least one
additional, clinically relevant chronic disease. Those with the most severe airflow obstruction …
additional, clinically relevant chronic disease. Those with the most severe airflow obstruction …
WHO working definition of vitality capacity for healthy longevity monitoring
Intrinsic capacity, a crucial concept in healthy ageing, is defined by WHO as" the composite
of all the physical and mental capacities that an individual can draw on at any point in time" …
of all the physical and mental capacities that an individual can draw on at any point in time" …
Association between life purpose and mortality among US adults older than 50 years
Importance A growing body of literature suggests that having a strong sense of purpose in
life leads to improvements in both physical and mental health and enhances overall quality …
life leads to improvements in both physical and mental health and enhances overall quality …
Determinants of muscle and bone aging
Loss of bone and muscle with advancing age represent a huge threat to loss of
independence in later life. Osteoporosis represents a major public health problem through …
independence in later life. Osteoporosis represents a major public health problem through …
Potential implications of polyphenols on aging considering oxidative stress, inflammation, autophagy, and gut microbiota
M Wu, Q Luo, R Nie, X Yang, Z Tang… - Critical reviews in food …, 2021 - Taylor & Francis
Naturally occurring compounds polyphenols are secondary metabolites of plants, comprised
several categories, namely, flavonoids, phenolic acids, lignans and stilbenes. The biological …
several categories, namely, flavonoids, phenolic acids, lignans and stilbenes. The biological …
Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype
Background Because chronic obstructive pulmonary disease (COPD) is a heterogeneous
condition, the identification of specific clinical phenotypes is key to develo** more effective …
condition, the identification of specific clinical phenotypes is key to develo** more effective …
Ageing and inflammation in patients with HIV infection
Nowadays, HIV+ patients have an expected lifespan that is only slightly shorter than healthy
individuals. For this reason, along with the fact that infection can be acquired at a relatively …
individuals. For this reason, along with the fact that infection can be acquired at a relatively …
Chronic obstructive pulmonary disease phenotypes: the future of COPD
Significant heterogeneity of clinical presentation and disease progression exists within
chronic obstructive pulmonary disease (COPD). Although FEV1 inadequately describes this …
chronic obstructive pulmonary disease (COPD). Although FEV1 inadequately describes this …
Understanding how we age: insights into inflammaging
Inflammaging is characterized by the upregulation of the inflammatory response that occurs
with advancing age; its roots are strongly embedded in evolutionary theory. Inflammaging is …
with advancing age; its roots are strongly embedded in evolutionary theory. Inflammaging is …