A review of clinical trials of anti-VEGF agents for diabetic retinopathy

BP Nicholson, AP Schachat - Graefe's Archive for Clinical and …, 2010 - Springer
Background Diabetic retinopathy (DR) is a leading cause of vision loss in the working-age
population worldwide. Many observational and preclinical studies have implicated vascular …

Anti‐vascular endothelial growth factor for prevention of postoperative vitreous cavity haemorrhage after vitrectomy for proliferative diabetic retinopathy

JM Smith, DHW Steel - Cochrane Database of Systematic …, 2015 - cochranelibrary.com
Background Postoperative vitreous cavity haemorrhage (POVCH) is a significant
complication following vitrectomy for proliferative diabetic retinopathy (PDR). It delays visual …

Anti-vascular endothelial growth factor therapy for proliferative diabetic retinopathy: a systematic review and meta-analysis

MP Simunovic, DAL Maberley - Retina, 2015 - journals.lww.com
Purpose: To systematically review and perform meta-analysis on the available randomized
controlled trial data for anti-vascular endothelial growth factor (anti-VEGF) agents in the …

Diabetic retinopathy: an update

R Singh, K Ramasamy, C Abraham… - Indian journal of …, 2008 - journals.lww.com
Diabetes mellitus is a major cause of avoidable blindness in both the develo** and the
developed countries. Significant technological advances have taken place to improve the …

The effect of adjunctive intravitreal bevacizumab for preventing postvitrectomy hemorrhage in proliferative diabetic retinopathy

J Ahn, SJ Woo, H Chung, KH Park - Ophthalmology, 2011 - Elsevier
OBJECTIVE: To assess the effects of preoperative and intraoperative intravitreal
bevacizumab (IVB) injection on the incidence of postoperative vitreous hemorrhage (VH) …

A systematic review and meta-analysis of clinical outcomes of vitrectomy with or without intravitreal bevacizumab pretreatment for severe diabetic retinopathy

LQ Zhao, H Zhu, PQ Zhao, YQ Hu - British journal of ophthalmology, 2011 - bjo.bmj.com
Aims To examine possible benefits of intravitreal bevacizumab (IVB) pretreatment in
vitrectomy for severe diabetic retinopathy. Methods A comprehensive literature search was …

Visual and anatomical outcomes following vitrectomy for complications of diabetic retinopathy: the DRIVE UK study

B Gupta, S Sivaprasad, R Wong, A Laidlaw… - Eye, 2012 - nature.com
Materials and methods This study identified the patients who underwent vitrectomy from
January 2007 to December 2009 because of diabetes-related complications in South East …

Antivascular endothelial growth factor agents pretreatment before vitrectomy for complicated proliferative diabetic retinopathy: a meta-analysis of randomised …

X Zhao, S **a, Y Chen - British Journal of Ophthalmology, 2018 - bjo.bmj.com
Background/aims To evaluate the efficacy of antivascular endothelial growth factor (anti-
VEGF) agents pretreatment before vitrectomy for patients with complicated proliferative …

Surgical management of the late complications of proliferative diabetic retinopathy

DK Newman - Eye, 2010 - nature.com
The late complications of proliferative diabetic retinopathy (PDR) comprise vitreous
haemorrhage, tractional retinal detachment, combined tractional–rhegmatogenous retinal …

Vitrectomy with or without preoperative intravitreal bevacizumab for proliferative diabetic retinopathy: a meta-analysis of randomized controlled trials

ZH Zhang, HY Liu, SE Hernandez-Da Mota… - American journal of …, 2013 - Elsevier
PURPOSE: To compare safety and functional outcomes of vitrectomy with or without
preoperative intravitreal bevacizumab (IVB) for proliferative diabetic retinopathy (PDR) …