Triggering receptor expressed on myeloid cells 2 (TREM2) is a single-pass transmembrane
immune receptor that is mainly expressed on microglia in the brain and macrophages in the …

Alzheimer's disease (AD) is a neurodegenerative disorder associated with cognitive decline.
Despite worldwide efforts to find a cure, no proper treatment has been developed yet, and …

Obesity, a burgeoning global health issue, is increasingly recognized for its detrimental
effects on the central nervous system, particularly concerning the integrity of the blood-brain …

Aging plays a pivotal role in the pathogenesis of cerebral small vessel disease (CSVD),
contributing to the onset and progression of vascular cognitive impairment and dementia …

Quantum dots (QDs) are semiconductor nanocrystals possessing unique optoelectrical
properties in that they can emit light energy of specific tunable wavelengths when excited by …

The hippocampus is a critical brain substrate for learning and memory; events that harm the
hippocampus can seriously impair mental and behavioral functioning. Hippocampal …

Ketone bodies are crucial intermediate metabolites widely associated with treating
metabolic diseases. Accumulating evidence suggests that ketone bodies may act as …

Background Blood–brain barrier (BBB) dysfunction is supposed to be an early event in the
development of Alzheimer's disease (AD). This study aimed to investigate the relationship …

It has been well recognized that intake of diets rich in saturated fats could result in
development of metabolic disorders such as type 2 diabetes mellitus, obesity and …

Background Diabetes has been recognized as a risk factor contributing to the incidence and
progression of Parkinson's disease (PD). Although several hypotheses suggest a number of …