Peptides are a growing therapeutic class due to their unique spatial characteristics that can
target traditionally “undruggable” protein–protein interactions and surfaces. Despite their …

The copper‐catalyzed azide/alkyne cycloaddition reaction (CuAAC) has emerged as the
most useful “click” chemistry. Polymer science has profited enormously from CuAAC by its …

This review emphasizes on the efficacy of various metals in their diverse oxidation states to
efficiently sew terminal alkyne to azide to give triazole ring. The emergence of Alkyne-Azide …

Abstract The use of 'Click Reaction'for Cu (I) catalyzed azide–alkyne cycloaddition (CuAAC)
has emerged as one of the most powerful tools for the synthesis of library of organic …

In the search for establishing a clickable copper‐catalysed (3+ 2) Huisgen azide–alkyne
cycloaddition (CuAAC) reaction under strict conditions, in particular in terms of preventing …

A series of Cu (I)-enriched metal–organic frameworks (MOF) of the type CuBTC (BTC=
benzene-1, 3, 5-tricarboxylate) was prepared by a mixed-linker defect engineering …

Stabilization of Cu (I) is ubiquitous within native copper proteins. Understanding how to
stabilize Cu (I) within synthetic biomimetic systems is therefore desired towards biological …

Peptide–drug conjugates (PDCs) have recently emerged as interesting hybrid constructs not
only for targeted therapy, but also for the early diagnosis of different pathologies. In most …

Reproducing the key features offered by metalloprotein binding cavities is an attractive
approach to overcome the main bottlenecks of current open artificial models (in terms of …

In the last two decades, click chemistry has become a modular synthetic procedure to
assemble new molecular structures. It is a powerful methodology that relies on the …